Literature DB >> 17258459

Rational design and synthesis of novel nucleotide anti-Giardia agents.

Dae-Hwan Suk1, Laurent Bonnac, Christine C Dykstra, Krzysztof W Pankiewicz, Steven E Patterson.   

Abstract

Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

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Year:  2007        PMID： 17258459     DOI： 10.1016/j.bmcl.2007.01.014

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Phosphonoxins III: synthesis of α-aminophosphonate analogs of antifungal polyoxins with anti-Giardia activity.

Authors:  Michael Staake; Jay Chauhan; Ding Zhou; Aaron Shanker; Atasi De Chatterjee; Siddhartha Das; Steven E Patterson
Journal:  Org Lett       Date:  2010-10-15       Impact factor: 6.005

2.  Synthesis of 5'-methylene-phosphonate furanonucleoside prodrugs: application to D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl nucleosides.

Authors:  Ugo Pradere; Franck Amblard; Steven J Coats; Raymond F Schinazi
Journal:  Org Lett       Date:  2012-08-23       Impact factor: 6.005
  2 in total

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