Literature DB >> 17257375

Establishment and characterization of a cell line (NABCA) derived from metastatic lymph nodes of breast scirrhous carcinoma.

Satoshi Ohi1, Shigeya Kyoda, Isao Tabei, Kouzou Ninomiya, Kayoko Sugiyama, Hisashi Hashimoto, Toshiaki Tachibana, Hiroshi Ishikawa.   

Abstract

We successfully established a breast scirrhous carcinoma cell line (designated as NABCA) derived from metastatic tumors of the lymph node. The cells grew as multi-layered cultures without contact inhibition. The population doubling time was approximately 66 h. G-band karyotype of NABCA revealed 66% diploid, XX. Surprisingly, the cells had a number of secretory granules and straight microvilli as a brash border. In heterotransplantation, the cells produced a tumor resembling the original tumor. The NABCA is sensitive to Adriamycin (doxorubicin; KYOWA HAKKO KOGYO, Tokyo, Japan) and Taxol (paclitaxel; Bristol-Myers KK, Tokyo, Japan). This cell line is useful for studying the mechanism of lymphatic metastasis and susceptibility of anticancer drugs in human breast scirrhous cancer.

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Year:  2006        PMID： 17257375     DOI： 10.1111/j.1749-0774.2006.00020.x

Source DB:  PubMed          Journal:  Hum Cell        ISSN： 0914-7470            Impact factor:   4.174


  9 in total

Review 1.  Measuring respiration of cultured cell with oxygen electrode as a metabolic indicator for drug screening.

Authors:  Y Amano; C Okumura; M Yoshida; H Katayama; S Unten; J Arai; T Tagawa; S Hoshina; H Hashimoto; H Ishikawa
Journal:  Hum Cell       Date:  1999-03       Impact factor: 4.174

2.  MCF-7: the first hormone-responsive breast cancer cell line.

Authors:  A S Levenson; V C Jordan
Journal:  Cancer Res       Date:  1997-08-01       Impact factor: 12.701

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Authors:  T Sawada; Y S Chung; B Nakata; T Kubo; Y Kondo; T Sogabe; N Onoda; Y Ogawa; N Yamada; M Sowa
Journal:  Hum Cell       Date:  1994-09       Impact factor: 4.174

4.  Differential tumorigenicity of two autologous human breast carcinoma cell lines, HMT-3909S1 and HMT-3909S8, established in serum-free medium.

Authors:  O W Petersen; B van Deurs; K V Nielsen; M W Madsen; I Laursen; I Balslev; P Briand
Journal:  Cancer Res       Date:  1990-02-15       Impact factor: 12.701

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Authors:  A Leibovitz; J Wymer; K Massey; F H Thompson; M A Nelson
Journal:  Cancer Lett       Date:  1994-07-29       Impact factor: 8.679

6.  Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node.

Authors:  M L Mahacek; D G Beer; T S Frank; S P Ethier
Journal:  Breast Cancer Res Treat       Date:  1993-12       Impact factor: 4.872

7.  Establishment and characterization of a new cell line from primary human breast carcinoma.

Authors:  D Amadori; L Bertoni; A Flamigni; S Savini; C De Giovanni; S Casanova; F De Paola; A Amadori; E Giulotto; W Zoli
Journal:  Breast Cancer Res Treat       Date:  1993-12       Impact factor: 4.872

8.  Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media.

Authors:  S P Ethier; M L Mahacek; W J Gullick; T S Frank; B L Weber
Journal:  Cancer Res       Date:  1993-02-01       Impact factor: 12.701

9.  Tumor progression in four mammary epithelial cell lines derived from the same patient.

Authors:  V Band; D Zajchowski; K Swisshelm; D Trask; V Kulesa; C Cohen; J Connolly; R Sager
Journal:  Cancer Res       Date:  1990-11-15       Impact factor: 12.701
  9 in total
  2 in total

1.  Existence of Neural Stem Cells in Mouse Spleen.

Authors:  Koichi Tomita; Hiroshi Ishikawa
Journal:  ScientificWorldJournal       Date:  2019-01-09

2.  Establishment and characterization of HER2-positive cell line derived from pleural effusion of human breast scirrhous carcinoma.

Authors:  Isao Tabei; Shigeki Nishiyama; Shigeo Yamashita; Hisashi Hashimoto; Toshiaki Tachibana; Ken Uchida; Hiroshi Ishikawa
Journal:  Hum Cell       Date:  2008-11       Impact factor: 4.374
  2 in total

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