AIM: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis. MATERIAL AND METHODS: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models. RESULTS: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use. CONCLUSIONS: Statin use was not associated with either a decreased or an increased risk of tooth loss.
AIM: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis. MATERIAL AND METHODS: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models. RESULTS: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use. CONCLUSIONS: Statin use was not associated with either a decreased or an increased risk of tooth loss.
Authors: Sharath Subramanian; Hamed Emami; Esad Vucic; Parmanand Singh; Jayanthi Vijayakumar; Kenneth M Fifer; Achilles Alon; Sudha S Shankar; Michael Farkouh; James H F Rudd; Zahi A Fayad; Thomas E Van Dyke; Ahmed Tawakol Journal: J Am Coll Cardiol Date: 2013-09-24 Impact factor: 24.094