Literature DB >> 17255648

Evaluation and management of the fat leg syndrome.

Anne G Warren1, Brian A Janz, Loren J Borud, Sumner A Slavin.   

Abstract

LEARNING
OBJECTIVES: After studying this article, the participant should be able to: 1. Discuss the initial evaluation of a patient presenting with lower extremity enlargement. 2. Distinguish underlying medical conditions causing lower extremity enlargement, including lymphedema and lipedema. 3. Discuss appropriate management and treatment for patients presenting with these conditions.
BACKGROUND: Given the epidemic of obesity in the United States, many patients will consult the plastic surgeon with complaints of lower extremity enlargement secondary to "fat legs." In addition to cosmetic disfigurement, some patients may suffer from underlying medical conditions that are responsible for their symptoms. Knowledge of these other causes, including lymphedema and a disorder of abnormal fat deposition known as lipedema, ensures appropriate management and/or surgical treatment for affected patients.
METHODS: Initial evaluation for lower extremity enlargement should include a discussion of pertinent medical history and a focused physical examination for findings that might indicate a pathologic underlying cause. When indicated, patients should undergo additional testing, including radiologic studies, to confirm their diagnoses.
RESULTS: For those patients found to have lymphatic dysfunction, conservative management, such as massage therapy, use of compression garments, and limb elevation, should be initially recommended. Excisional or suction-assisted lipectomy may be considered in patients who fail conservative therapy. More extensive consultation with the plastic surgeon is recommended for patients seeking aesthetic improvement in contour and shape of large legs without a specified underlying abnormality.
CONCLUSIONS: Patients with lower extremity enlargement may present to the plastic surgeon unsure of the specific cause of their deformity. A broad differential diagnosis exists for their presentation, which can be narrowed by using the common features and unique manifestations of the conditions.

Entities:  

Mesh:

Year:  2007        PMID: 17255648     DOI: 10.1097/01.prs.0000244909.82805.dc

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  6 in total

Review 1.  Rare adipose disorders (RADs) masquerading as obesity.

Authors:  Karen L Herbst
Journal:  Acta Pharmacol Sin       Date:  2012-02       Impact factor: 6.150

Review 2.  Lipedema-Pathogenesis, Diagnosis, and Treatment Options.

Authors:  Philipp Kruppa; Iakovos Georgiou; Niklas Biermann; Lukas Prantl; Peter Klein-Weigel; Mojtaba Ghods
Journal:  Dtsch Arztebl Int       Date:  2020-06-01       Impact factor: 5.594

Review 3.  The MMP14-caveolin axis and its potential relevance for lipoedema.

Authors:  Ilja L Kruglikov; Nolwenn Joffin; Philipp E Scherer
Journal:  Nat Rev Endocrinol       Date:  2020-08-13       Impact factor: 43.330

Review 4.  Lipedema: diagnostic and management challenges.

Authors:  Anne Warren Peled; Elisabeth A Kappos
Journal:  Int J Womens Health       Date:  2016-08-11

5.  A Multi-Gene Panel to Identify Lipedema-Predisposing Genetic Variants by a Next-Generation Sequencing Strategy.

Authors:  Sandro Michelini; Karen L Herbst; Vincenza Precone; Elena Manara; Giuseppe Marceddu; Astrit Dautaj; Paolo Enrico Maltese; Stefano Paolacci; Maria Rachele Ceccarini; Tommaso Beccari; Elisa Sorrentino; Barbara Aquilanti; Valeria Velluti; Giuseppina Matera; Lucilla Gagliardi; Giacinto Abele Donato Miggiano; Matteo Bertelli
Journal:  J Pers Med       Date:  2022-02-11

Review 6.  Lipedema: A Call to Action!

Authors:  Giacomo Buso; Michele Depairon; Didier Tomson; Wassim Raffoul; Roberto Vettor; Lucia Mazzolai
Journal:  Obesity (Silver Spring)       Date:  2019-10       Impact factor: 5.002

  6 in total

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