Literature DB >> 17254579

Increase of multiple pregnancies caused by ovulation induction with gonadotropin in combination with metformin in infertile women with polycystic ovary syndrome.

Hiroaki Shibahara1, Kumiko Kikuchi, Yuki Hirano, Tatsuya Suzuki, Satoru Takamizawa, Mitsuaki Suzuki.   

Abstract

Metformin appears to be an effective medicine to induce ovulation in women with polycystic ovary syndrome and insulin resistance. After the introduction of metformin treatment for such cases, the use of gonadotropin in combination with metformin significantly increased the incidence of multiple pregnancies.

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Year:  2007        PMID： 17254579     DOI： 10.1016/j.fertnstert.2006.11.021

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  2 in total

1.  Metformin use in patients undergoing in vitro fertilization treatment: results of a worldwide web-based survey.

Authors:  Mindy S Christianson; Harold Wu; Yulian Zhao; Matan Yemini; Milton Leong; Zeev Shoham
Journal:  J Assist Reprod Genet       Date:  2015-01-30       Impact factor: 3.412

Review 2.  Metformin during ovulation induction with gonadotrophins followed by timed intercourse or intrauterine insemination for subfertility associated with polycystic ovary syndrome.

Authors:  Esmée M Bordewijk; Marleen Nahuis; Michael F Costello; Fulco Van der Veen; Leopoldo O Tso; Ben Willem J Mol; Madelon van Wely
Journal:  Cochrane Database Syst Rev       Date:  2017-01-24
  2 in total

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