| Literature DB >> 17253831 |
Yolanda Arroyo1, J Félix Rodríguez, Mercedes Santos, M Ascensión Sanz Tejedor, José Luis García Ruano.
Abstract
Reactions of (S)-alpha-(methylthio)-2-(p-tolylsulfinyl)benzyl carbanion with different carbonyl compounds proceeds with complete control of the configuration at the benzylic position. Aldehydes yield easily separable mixtures of beta-hydroxy sulfides, epimers at the hydroxylic carbon, where the stereoselectivity depends on steric factors (from 20% to >98% de).Entities:
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Year: 2007 PMID： 17253831 DOI： 10.1021/jo062053q
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354