Literature DB >> 17253795

Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2).

Irene Fotakopoulou1, Efrosini Barbayianni, Violetta Constantinou-Kokotou, Uwe T Bornscheuer, George Kokotos.   

Abstract

An esterase from Bacillus subtilis (BS2) allows the fast and selective removal of allyl, 2-chloroethyl, and 2,2,2-chloroethyl esters under mild conditions in high yields. In addition, BS2 easily hydrolyzes phenacyl esters, while the hydrolysis of sterically hindered diphenylmethyl esters is slow, requiring longer reaction time and higher enzyme/substrate ratio.

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Year:  2007        PMID: 17253795     DOI: 10.1021/jo061871f

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  The microbiota is essential for the generation of black tea theaflavins-derived metabolites.

Authors:  Huadong Chen; Saeed Hayek; Javier Rivera Guzman; Nicholas D Gillitt; Salam A Ibrahim; Christian Jobin; Shengmin Sang
Journal:  PLoS One       Date:  2012-12-05       Impact factor: 3.240

2.  Phage-Assisted Continuous Evolution and Selection of Enzymes for Chemical Synthesis.

Authors:  Krysten A Jones; Harrison M Snodgrass; Ketaki Belsare; Bryan C Dickinson; Jared C Lewis
Journal:  ACS Cent Sci       Date:  2021-09-13       Impact factor: 14.553

  2 in total

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