Literature DB >> 17252884

Prediction of uvulopalatopharyngoplasty outcome: anatomy-based staging system versus severity-based staging system.

Hsueh-Yu Li1, Pa-Chun Wang, Li-Ang Lee, Ning-Hung Chen, Tuan-Jen Fang.   

Abstract

STUDY
OBJECTIVE: To evaluate and compare outcomes of uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea/hypopnea syndrome (OSAHS) using anatomy- and severity-based staging systems.
DESIGN: Prospective design with a retrospective review.
SETTING: A tertiary-care, sleep disorder referral center. PATIENTS: In total, 110 patients with OSAHS (105 men, 5 women; mean age, 43 years; apnea-hypopnea index, 44.4 +/- 28.8 events per hour; body mass index, 27.1 +/- 3.3 kg/m2). MEASUREMENTS: An anatomy-based staging system (stages I-IV) was used to classify patients with OSAHS by examining tongue-palate position, tonsil size, body mass index, and craniofacial deformities. Patients were also classified as having mild, moderate, moderate-severe, or severe OSAHS based on preoperative apnea-hypopnea index from polysomnography (a severity-based staging system). Surgical success was defined as a 50% or greater reduction in the apnea-hypopnea index and a postoperative apnea-hypopnea index of less than 20 events per hour. INTERVENTION: UPPP was performed in all patients.
RESULTS: The overall success rate of UPPP was 78%. Success rates for mild (90%), moderate (73%), moderate-severe (81%), and severe (74%) diseases were similar (p = .10). Conversely, success rates for patients with anatomy-based stages I, II, III, and IV were 100%, 96%, 65%, and 20%, respectively; these rates were significantly different (p < .001). Changes in apnea-hypopnea index were significantly correlated with Friedman tongue position (FTP) (r = -0.33, p = .0004) and tonsil size (r = -0.37, p < .0001). The FTP (odds ratio = 0.43, SE = 0.13, p = .005, 95% confidence interval = 0.24-0.78) and tonsil size (odds ratio = 3.13, SE = 1.53, p = .02, 95% confidence interval = 1.20-8.17), but not the severity-based staging (odds ratio = 0.77, SE = 0.18, p = .283, 95% confidence interval = 0.49-1.23), were predictive of surgical success.
CONCLUSION: The anatomy-based staging system predicted UPPP outcomes more effectively than did the severity-based staging. The anatomy-based staging system facilitates good case-selection information for counseling patients before UPPP surgery.

Entities:  

Mesh:

Year:  2006        PMID: 17252884     DOI: 10.1093/sleep/29.12.1537

Source DB:  PubMed          Journal:  Sleep        ISSN: 0161-8105            Impact factor:   5.849


  28 in total

1.  [Endoscopy in sleep medicine].

Authors:  J T Maurer; K Hörmann
Journal:  HNO       Date:  2010-04       Impact factor: 1.284

Review 2.  [Update on upper airway evaluation in obstructive sleep apnea].

Authors:  J T Maurer; B A Stuck
Journal:  HNO       Date:  2008-11       Impact factor: 1.284

Review 3.  [Modern modifications of uvulopalatopharyngoplasty].

Authors:  T Verse; B A Stuck
Journal:  HNO       Date:  2017-02       Impact factor: 1.284

Review 4.  Palate surgery for obstructive sleep apnea: a 17-year meta-analysis.

Authors:  Kenny Peter Pang; Guillermo Plaza; Peter M Baptista J; Carlos O'Connor Reina; Yiong Huak Chan; Kathleen A Pang; Edward B Pang; Cybil Mei Zhi Wang; Brian Rotenberg
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-05-25       Impact factor: 2.503

5.  Physiology-Based Modeling May Predict Surgical Treatment Outcome for Obstructive Sleep Apnea.

Authors:  Yanru Li; Jingying Ye; Demin Han; Xin Cao; Xiu Ding; Yuhuan Zhang; Wen Xu; Jeremy Orr; Rachel Jen; Scott Sands; Atul Malhotra; Robert Owens
Journal:  J Clin Sleep Med       Date:  2017-09-15       Impact factor: 4.062

6.  Statistical model for postoperative apnea-hypopnea index after multilevel surgery for sleep-disordered breathing.

Authors:  Kurt Tschopp; Thomas Zumbrunn; Christoph Knaus; Esther Thomaser; Thomas Fabbro
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-04-07       Impact factor: 2.503

7.  Associated predictors of therapeutic response to uvulopharyngopalatoplasty for severe obstructive sleep apnea hypopnea syndrome.

Authors:  Su Ru Liu; Hong Liang Yi; Shan Kai Yin; Jian Guan; Bin Chen; Li Li Meng; Kai Ming Su
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-02-27       Impact factor: 2.503

8.  Complete concentric collapse at the soft palate in sleep endoscopy: what change is possible after UPPP in patients with CPAP failure?

Authors:  Katrin Hasselbacher; A Seitz; N Abrams; B Wollenberg; A Steffen
Journal:  Sleep Breath       Date:  2018-05-16       Impact factor: 2.816

9.  Single-session radiofrequency tongue base reduction combined with uvulopalatopharyngoplasty for obstructive sleep apnea syndrome.

Authors:  Young Gyu Eun; Sung Wan Kim; Kee Hwan Kwon; Jae Yong Byun; Kun Hee Lee
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-04-29       Impact factor: 2.503

10.  Obstructive site localization using multisensor manometry versus the Friedman staging system in obstructive sleep apnea.

Authors:  Chul Hee Lee; Tae-Bin Won; Wonjae Cha; In Young Yoon; Seockhoon Chung; Jeong-Whun Kim
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-08-28       Impact factor: 2.503

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