Literature DB >> 17252381

Cytotoxic sterols from the formosan brown alga Turbinaria ornata.

J H Sheu, G H Wang, P J Sung, Y H Chiu, C Y Duh.   

Abstract

Two hydroperoxysterols 24-hydroperoxy-24-vinyl-cholesterol (1) and 29-hydroperoxystigmasta-5,24(28)-dien-3beta-ol (2), and fucosterol (3) were isolated from the brown alga Turbinaria ornata (Sargassaceae). Hydroperoxide 2 is a new natural compound and was converted into 29-hydroxystigmasta-5,24 (28)-dien-3beta-ol (4) by reaction with LAH. Sterols 1, 2, and 4 exhibited cytotoxicity against various cancer cell lines.

Entities:  

Year:  1997        PMID: 17252381     DOI: 10.1055/s-2006-957772

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  9 in total

1.  Acute toxicity study and antipyretic effect of the brown alga Turbinaria conoides (J. Agardh) Kuetz.

Authors:  S Sadish Kumar; Y Kumar; M S Y Khan; J Anbu; K G Sam
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-05-07

2.  In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts.

Authors:  Souleymane Fofana; Cédric Delporte; Rafaèle Calvo Esposito; Moussa Ouédraogo; Pierre Van Antwerpen; Innocent Pierre Guissou; Rasmané Semdé; Véronique Mathieu
Journal:  Molecules       Date:  2022-04-16       Impact factor: 4.927

Review 3.  Advances in Microalgae-Derived Phytosterols for Functional Food and Pharmaceutical Applications.

Authors:  Xuan Luo; Peng Su; Wei Zhang
Journal:  Mar Drugs       Date:  2015-07-09       Impact factor: 5.118

4.  Antimicrobial and cytotoxic activities of turbinariaconoides (j.agardh) kuetz.

Authors:  Sadish Kumar Shanmugam; Yatendra Kumar; Khan Mohammad Sardaryar; Vivek Gupta; Erik De Clercq
Journal:  Iran J Pharm Res       Date:  2010       Impact factor: 1.696

5.  Bioactive chemical constituents from the brown alga Homoeostrichus formosana.

Authors:  Hui-Yu Fang; Uvarani Chokkalingam; Shu-Fen Chiou; Tsong-Long Hwang; Shu-Li Chen; Wei-Lung Wang; Jyh-Horng Sheu
Journal:  Int J Mol Sci       Date:  2014-12-30       Impact factor: 5.923

6.  Fucosterol Suppresses the Progression of Human Ovarian Cancer by Inducing Mitochondrial Dysfunction and Endoplasmic Reticulum Stress.

Authors:  Hyocheol Bae; Jin-Young Lee; Gwonhwa Song; Whasun Lim
Journal:  Mar Drugs       Date:  2020-05-16       Impact factor: 5.118

7.  A cytotoxic hydroperoxy sterol from the brown alga, Nizamuddinia zanardinii.

Authors:  Maryam Hamzeloo Moghadam; Jamileh Firouzi; Soodabeh Saeidnia; Homa Hajimehdipoor; Shahla Jamili; Abdolhossein Rustaiyan; Ahmad R Gohari
Journal:  Daru       Date:  2013-03-18       Impact factor: 3.117

8.  Standardized Fraction of Turbinaria ornata Alleviates Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice via Upregulation of FOXP3+ Regulatory T Cells.

Authors:  Na-Hyun Kim; Seon Min Lee; Yun Na Kim; You-Jin Jeon; Jeong-Doo Heo; Eun Ju Jeong; Jung-Rae Rho
Journal:  Biomolecules       Date:  2020-10-20

Review 9.  Natural Products Repertoire of the Red Sea.

Authors:  Ebaa M El-Hossary; Mohammad Abdel-Halim; Eslam S Ibrahim; Sheila Marie Pimentel-Elardo; Justin R Nodwell; Heba Handoussa; Miada F Abdelwahab; Ulrike Holzgrabe; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2020-09-04       Impact factor: 5.118

  9 in total

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