Literature DB >> 17252110

One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction.

Hao Li1, Jian Wang, Timiyin E-Nunu, Liansuo Zu, Wei Jiang, Shaohua Wei, Wei Wang.   

Abstract

A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of alpha,beta-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.

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Year:  2006        PMID： 17252110     DOI： 10.1039/b611502k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions.

Authors:  Shi-Lei Zhang; He-Xin Xie; Jin Zhu; Hao Li; Xin-Shuai Zhang; Jian Li; Wei Wang
Journal:  Nat Commun       Date:  2011       Impact factor: 14.919

2.  An organocascade kinetic resolution.

Authors:  Patrick G McGarraugh; Stacey E Brenner-Moyer
Journal:  Org Lett       Date:  2011-11-15       Impact factor: 6.005

3.  Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts.

Authors:  Bhaskar C Das; Seetaram Mohapatra; Philip D Campbell; Sabita Nayak; Sakkarapalayam M Mahalingam; Todd Evans
Journal:  Tetrahedron Lett       Date:  2010-05-01       Impact factor: 2.415

4.  Organocatalytic Highly Enantioselective Tandem Michael-Knoevenagel Reaction for the Synthesis of Substituted Thiochromanes.

Authors:  Rajasekhar Dodda; Tanmay Mandal; Cong-Gui Zhao
Journal:  Tetrahedron Lett       Date:  2008-03-17       Impact factor: 2.415

5.  Synthesis of 2,3,4-Trisubstituted Thiochromanes using an Organocatalytic Enantioselective Tandem Michael-Henry Reaction.

Authors:  Rajasekhar Dodda; Joshua J Goldman; Tanmay Mandal; Cong-Gui Zhao; Grant A Broker; Edward R T Tiekink
Journal:  Adv Synth Catal       Date:  2008-02-26       Impact factor: 5.837

6.  Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines.

Authors:  Chittaranjan Bhanja; Satyaban Jena; Sabita Nayak; Seetaram Mohapatra
Journal:  Beilstein J Org Chem       Date:  2012-10-04       Impact factor: 2.883
  6 in total

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