Literature DB >> 17251920

A mesothelioma epidemic in Cappadocia: scientific developments and unexpected social outcomes.

Michele Carbone1, Salih Emri, A Umran Dogan, Ian Steele, Murat Tuncer, Harvey I Pass, Y Izzettin Baris.   

Abstract

In Cappadocia, Turkey, an unprecedented mesothelioma epidemic causes 50% of all deaths in three small villages. Initially linked solely to the exposure to a fibrous mineral, erionite, recent studies by scientists from Turkey and the United States have shown that erionite causes mesothelioma mostly in families that are genetically predisposed to mineral fibre carcinogenesis. This manuscript reports, through the eyes of one of the researchers, the resulting scientific advances that have come from these studies and the social improvements that were brought about by both the scientists and members of the Turkish Government.

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Year:  2007        PMID: 17251920     DOI: 10.1038/nrc2068

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  59 in total

Review 1.  Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma.

Authors:  Roberto E Favoni; Antonio Daga; Paolo Malatesta; Tullio Florio
Journal:  Br J Pharmacol       Date:  2012-05       Impact factor: 8.739

2.  Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma.

Authors:  Michele Carbone; Haining Yang
Journal:  Clin Cancer Res       Date:  2011-11-07       Impact factor: 12.531

Review 3.  Diagnostic and prognostic biomarkers for malignant mesothelioma: an update.

Authors:  Zhongjian Chen; Giovanni Gaudino; Harvey I Pass; Michele Carbone; Haining Yang
Journal:  Transl Lung Cancer Res       Date:  2017-06

Review 4.  Malignant mesothelioma: facts, myths, and hypotheses.

Authors:  Michele Carbone; Bevan H Ly; Ronald F Dodson; Ian Pagano; Paul T Morris; Umran A Dogan; Adi F Gazdar; Harvey I Pass; Haining Yang
Journal:  J Cell Physiol       Date:  2012-01       Impact factor: 6.384

Review 5.  Mesothelioma: recent highlights.

Authors:  Michele Carbone; Haining Yang
Journal:  Ann Transl Med       Date:  2017-06

Review 6.  Environmental asbestos exposure and risk of mesothelioma.

Authors:  Curtis W Noonan
Journal:  Ann Transl Med       Date:  2017-06

Review 7.  The Cappadocia mesothelioma epidemic: its influence in Turkey and abroad.

Authors:  Salih A Emri
Journal:  Ann Transl Med       Date:  2017-06

8.  Receptor role of the annexin A2 in the mesothelial endocytosis of crocidolite fibers.

Authors:  Kyoko Yamashita; Hirotaka Nagai; Shinya Toyokuni
Journal:  Lab Invest       Date:  2015-04-27       Impact factor: 5.662

9.  Erionite series minerals: mineralogical and carcinogenic properties.

Authors:  A Umran Dogan; Meral Dogan; John A Hoskins
Journal:  Environ Geochem Health       Date:  2008-03-18       Impact factor: 4.609

10.  Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma.

Authors:  Camillo Porta; Chiara Paglino; Luciano Mutti
Journal:  Biologics       Date:  2008-12
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