Literature DB >> 17250954

Significance of aortic atheroma in elderly patients with ischemic stroke. A hospital-based study and literature review.

Mohamad Bagher Sharifkazemi1, Amir Aslani, Mahmood Zamirian, Ali Reza Moaref.   

Abstract

OBJECTIVES: Cardioembolism accounts for 15-30% of ischemic strokes. Transesophageal echocardiography (TEE) is useful in detecting potential sources of cardiac embolism. Aortic atheromas have recently been recognized as important causes of stroke. The aim of this study was to evaluate TEE findings in elderly patients with ischemic stroke. A review of literature was done to highlight the significance of aortic atherosclerotic disease in patients with ischemic stroke.
METHODS: One hundred consecutive patients with ischemic stroke aged > or =55 years underwent TEE for evaluation of cardiac sources of embolism. Patients with significant carotid artery stenosis (stenosis of >50% in common or internal carotid arteries) were excluded.
RESULTS: The most noteworthy finding was the high prevalence of complex atheromatous plaques in the ascending aorta and/or aortic arch (25%).
CONCLUSION: The present study demonstrates that TEE is helpful to detect cardiovascular sources of embolism in elderly patients with ischemic stroke. Aortic atheroma is present in 25% of elderly patients with ischemic stroke and without significant carotid artery stenosis. Aortic atherosclerosis may be an important cause of ischemic stroke in this population.

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Year:  2007        PMID: 17250954     DOI: 10.1016/j.clineuro.2006.12.003

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  5 in total

1.  Impact of cystatin C levels on infarct size and hemorrhage volume in acute cerebral stroke.

Authors:  Dongfang Xiao; Hailong Liu; Hong Zhang; Yumin Luo
Journal:  J Neurol       Date:  2012-02-18       Impact factor: 4.849

Review 2.  Association Between Cystatin C and the Risk of Ischemic Stroke: a Systematic Review and Meta-analysis.

Authors:  Yan Wang; Wei Li; Jun Yang; Mijuan Zhang; Chun'e Tian; Minjiang Ma; Qian Zhang
Journal:  J Mol Neurosci       Date:  2019-07-17       Impact factor: 3.444

3.  Hyperlipidemia exacerbates cerebral injury through oxidative stress, inflammation and neuronal apoptosis in MCAO/reperfusion rats.

Authors:  Xiao-Lu Cao; Jing Du; Ying Zhang; Jing-Ting Yan; Xia-Min Hu
Journal:  Exp Brain Res       Date:  2015-08-04       Impact factor: 1.972

4.  Multiplane transesophageal echocardiography for multiclinical dilemmas.

Authors:  Lulzim S Kamberi; Daut R Gorani; Hajdin R Citaku; Hamza H Selmani; Arton I Beqiri; Ardian I Mustafai
Journal:  Acta Inform Med       Date:  2011-09

5.  Correlation between aortic/carotid atherosclerotic plaques and cerebral infarction.

Authors:  Baojun Wang; Shaoli Sun; Guorong Liu; Yuechun Li; Jiangxia Pang; Jingfen Zhang; Lijuan Yang; Ruiming Li; Hui Zhang; Changchun Jiang; Xiue Li
Journal:  Exp Ther Med       Date:  2013-05-23       Impact factor: 2.447

  5 in total

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