Literature DB >> 17249730

Synthesis of symmetrical and unsymmetrical pyrazines.

Douglass F Taber1, Peter W DeMatteo, Karen V Taluskie.   

Abstract

Opening of representative epoxides with 1,2-amino alcohols delivered the amino diols. The product amino diols were then oxidized under Swern conditions. The amino diketones so prepared were not isolated, but were condensed directly with hydroxylamine to give the substituted pyrazines.

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Year:  2007        PMID： 17249730      PMCID： PMC3251312          DOI： 10.1021/jo061935m

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

1.  Novel pyrazines from the head of Australian ponerine antRhytidoponera metallica.

Authors:  B Tecle; C M Sun; J J Brophy; R F Toia
Journal:  J Chem Ecol       Date:  1987-08       Impact factor: 2.626

2.  Facile regiocontrolled synthesis of trialkyl-substituted pyrazines.

Authors:  Tarek Abou Elmaaty; Lyle W Castle
Journal:  Org Lett       Date:  2005-11-24       Impact factor: 6.005

3.  Synthesis of pyrazine-phosphonates and -phosphine oxides from 2H-azirines or oximes.

Authors:  Francisco Palacios; Ana María Ochoa de Retana; José Ignacio Gil; Rafael López de Munain
Journal:  Org Lett       Date:  2002-07-11       Impact factor: 6.005

4.  Pyrazine derivatives affect membrane fluidity of vascular smooth muscle microsomes in relation to their biological activity.

Authors:  S Q Nie; C Y Kwan; R M Epand
Journal:  Eur J Pharmacol       Date:  1993-01-04       Impact factor: 4.432
  4 in total
  1 in total

1.  Synthesis of C14,15-dihydro-C22,25-epi north unit of cephalostatin 1 via "red-ox" modifications of hecogenin acetate.

Authors:  Seongmin Lee; Daniel Jamieson; Philip L Fuchs
Journal:  Org Lett       Date:  2009-01-01       Impact factor: 6.005
  1 in total

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