Literature DB >> 17248892

Viability of Homozygous Deficiencies in Somatic Cells of DROSOPHILA MELANOGASTER.

P Ripoll1, A García-Bellido.   

Abstract

The viability of cells made homozygous for different deficiencies by induced mitotic recombination was examined. The deficiencies varied in length from two to 30 polytene chromosome bands and were distributed over the five major chromosome arms. Among a sample of 30, ten deficiencies were cell viable. Our results show that 12% of the genome is necessary for cell survival, supporting previous estimates of about 5,000 genes in the genome of Drosophila.

Entities:  

Year:  1979        PMID： 17248892      PMCID： PMC1216842     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  18 in total

1.  Minutes: mutants of drosophila autonomously affecting cell division rate.

Authors:  G Morata; P Ripoll
Journal:  Dev Biol       Date:  1975-02       Impact factor: 3.582

2.  The Individual Gene in Relation to the Chromomere and the Chromosome.

Authors:  H J Muller; A A Prokofyeva
Journal:  Proc Natl Acad Sci U S A       Date:  1935-01       Impact factor: 11.205

3.  Evidence for a Sex-Linked Haplo-Inviable Locus in the Cut-Singed Region of DROSOPHILA MELANOGASTER.

Authors:  G Lefevre; T K Johnson
Journal:  Genetics       Date:  1973-08       Impact factor: 4.562

4.  Developmental Analysis of the Achaete-Scute System of DROSOPHILA MELANOGASTER.

Authors:  A García-Bellido; P Santamaria
Journal:  Genetics       Date:  1978-03       Impact factor: 4.562

Review 5.  Chromomeres and genes.

Authors:  W Beermann
Journal:  Results Probl Cell Differ       Date:  1972

6.  Clonal parameters of tergite development in Drosophila.

Authors:  A Garcia-Bellido; J R Merriam
Journal:  Dev Biol       Date:  1971-10       Impact factor: 3.582

7.  Analysis of chromosome 4 in Drosophila melanogaster. II. Ethyl methanesulfonate induced lethals.

Authors:  B Hochman
Journal:  Genetics       Date:  1971-02       Impact factor: 4.562

8.  Genetic duplication in the white-split interval of the X chromosome in Drosophila melanogaster.

Authors:  G Lefevre; M M Green
Journal:  Chromosoma       Date:  1972       Impact factor: 4.316

9.  Genetics of acetylcholinesterase in Drosophila melanogaster.

Authors:  J C Hall; D R Kankel
Journal:  Genetics       Date:  1976-07       Impact factor: 4.562

10.  Lethality patterns and morphology of selected lethal and semi-lethal mutations in the zeste-white region of Drosophila melanogaster.

Authors:  M P Shannon; T C Kaufman; M W Shen; B H Judd
Journal:  Genetics       Date:  1972-12       Impact factor: 4.562
View more
  11 in total

1.  Developmental use of gene products in Drosophila: the maternal-zygotic transition.

Authors:  L G Robbins
Journal:  Genetics       Date:  1984-10       Impact factor: 4.562

2.  Viability of Female Germ-Line Cells Homozygous for Zygotic Lethals in DROSOPHILA MELANOGASTER.

Authors:  A Garcia-Bellido; L G Robbins
Journal:  Genetics       Date:  1983-02       Impact factor: 4.562

3.  The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila.

Authors:  J Szabad; G Reuter; M B Schröder
Journal:  Mol Gen Genet       Date:  1988-01

4.  Recovery and Characterization of Temperature-Sensitive Mutations Affecting Adult Viability in DROSOPHILA MELANOGASTER.

Authors:  T Homyk; D A Sinclair; D T Wong; T A Grigliatti
Journal:  Genetics       Date:  1986-06       Impact factor: 4.562

5.  Molecular and genetic studies on the euchromatin-heterochromatin transition region of the X chromosome of Drosophila melanogaster. 1. A cloned entry point near to the uncoordinated (unc) locus.

Authors:  G L Miklos; M J Healy; P Pain; A J Howells; R J Russell
Journal:  Chromosoma       Date:  1984       Impact factor: 4.316

6.  The meiotic behavior of some single-cistron mutants in the zeste-white region of the Drosophila melanogaster X chromosome.

Authors:  L G Robbins
Journal:  Mol Gen Genet       Date:  1981

7.  Identification of genes affecting wing patterning through a loss-of-function mutagenesis screen and characterization of med15 function during wing development.

Authors:  Ana Terriente-Félix; Ana López-Varea; Jose F de Celis
Journal:  Genetics       Date:  2010-03-16       Impact factor: 4.562

8.  Temperature-sensitive lethal mutations on yeast chromosome I appear to define only a small number of genes.

Authors:  D B Kaback; P W Oeller; H Yde Steensma; J Hirschman; D Ruezinsky; K G Coleman; J R Pringle
Journal:  Genetics       Date:  1984-09       Impact factor: 4.562

9.  Overexpression of a Rrp1 transgene reduces the somatic mutation and recombination frequency induced by oxidative DNA damage in Drosophila melanogaster.

Authors:  A Szakmary; S M Huang; D T Chang; P A Beachy; M Sander
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-20       Impact factor: 11.205

10.  Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster.

Authors:  H M Thaker; D R Kankel
Journal:  Genetics       Date:  1992-08       Impact factor: 4.562
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.