Literature DB >> 17245490

System properties of ErbB receptor signaling for the understanding of cancer progression.

Mariko Hatakeyama1.   

Abstract

An intracellular signal transduction network constitutes an assembled machinery to control the dynamics of kinase-phosphatase cascade and gene expression. Spatio-temporal analyses of the cellular process can explain the biochemical role of the receptor tyrosine kinases in cancer development from a system point of view.

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Year:  2006        PMID： 17245490     DOI： 10.1039/b612800a

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  4 in total

1.  Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.

Authors:  Christopher P Mill; Kathleen L Gettinger; David J Riese
Journal:  Exp Cell Res       Date:  2010-11-24       Impact factor: 3.905

2.  Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network.

Authors:  Galina Lebedeva; Anatoly Sorokin; Dana Faratian; Peter Mullen; Alexey Goltsov; Simon P Langdon; David J Harrison; Igor Goryanin
Journal:  Eur J Pharm Sci       Date:  2011-11-09       Impact factor: 4.384

3.  GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness.

Authors:  Mateusz Zajac; Jeffrey Law; Dragana Donna Cvetkovic; Macarena Pampillo; Lindsay McColl; Cynthia Pape; Gianni M Di Guglielmo; Lynne M Postovit; Andy V Babwah; Moshmi Bhattacharya
Journal:  PLoS One       Date:  2011-06-28       Impact factor: 3.240

4.  Systems pharmacology and genome medicine: a future perspective.

Authors:  Aislyn D Wist; Seth I Berger; Ravi Iyengar
Journal:  Genome Med       Date:  2009-01-22       Impact factor: 11.117
  4 in total

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