Literature DB >> 172450

Effect of pretreatment with Mycobacterium bovis (strain BCG) and immune syphilitic serum on rabbit resistance to Treponema pallidum.

S R Graves, R C Johnson.   

Abstract

Stimulation of the rabbit reticuloendothelial system with viable Mycobacterium bovis (strain BCG), and other agents, had no effect on the development of syphilitic lesions after intradermal or intravenous inoculation with graded doses of Treponema pallidum (virulent Nichol's strain; mean infective doses less than 10). The simultaneous administration of immune syphilitic rabbit serum retarded the development of lesions, but this appeared to be due solely to the immune serum, suggesting no synergism between the activated reticuloendothelial system and the anti-T. pallidum antibodies. The administration of two doses of BCG enhanced syphilitic lesion development in the rabbit.

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Year:  1975        PMID: 172450      PMCID: PMC415393          DOI: 10.1128/iai.12.5.1029-1036.1975

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  32 in total

1.  ALTERATION OF RES PHAGOCYTIC FUNCTION BY PYROGEN CONTAMINATED COLLOIDAL CARBON.

Authors:  E E HANNA; D W WATSON
Journal:  Proc Soc Exp Biol Med       Date:  1965-04

2.  Protective layer covering pathogenic treponemata.

Authors:  S CHRISTIANSEN
Journal:  Lancet       Date:  1963-02-23       Impact factor: 79.321

3.  Tumour growth, phagocytic activity and antibody response in Corynebacterium parvum-treated mice.

Authors:  M F Woodruff; W H McBride; N Dunbar
Journal:  Clin Exp Immunol       Date:  1974-07       Impact factor: 4.330

4.  Serial ultrathin sectioning demonstrating the intracellularity of T. Pallidum. An electron microscopic study.

Authors:  V Lauderdale; J N Goldman
Journal:  Br J Vener Dis       Date:  1972-04

5.  Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.

Authors:  G M Levene; J L Turk; D J Wright; A G Grimble
Journal:  Lancet       Date:  1969-08-02       Impact factor: 79.321

6.  Enhanced resistance of mice to infection with bacteria following pre-treatment with Corynebacterium parvum.

Authors:  C Adlam; E S Broughton; M T Scott
Journal:  Nat New Biol       Date:  1972-02-16

7.  The immunoprotective niche--a new pathogenic mechanism for syphilis, the systemic mycoses and other infectious diseases.

Authors:  M A Medici
Journal:  J Theor Biol       Date:  1972-09       Impact factor: 2.691

8.  Nonspecific inhibition of growth of intracellular Listeria monocytogenes by lymphocyte culture products.

Authors:  T Jones; G P Youmans
Journal:  Infect Immun       Date:  1974-02       Impact factor: 3.441

9.  Detection of nonspecific resistance to Listeria monocytogenes in rabbits infected with Treponema pallidum.

Authors:  R F Schell; D M Musher
Journal:  Infect Immun       Date:  1974-04       Impact factor: 3.441

10.  Inhibition of multiplication of Toxoplasma gondii by human monocytes exposed to T-lymphocyte products.

Authors:  J S Borges; W D Johnson
Journal:  J Exp Med       Date:  1975-02-01       Impact factor: 14.307

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  14 in total

1.  Ability of macrophages to process and present Treponema pallidum Bosnia A strain antigens in experimental syphilis of syrian hamsters.

Authors:  O Bagasra; I Damjanov
Journal:  Infect Immun       Date:  1982-04       Impact factor: 3.441

2.  Activation of macrophages by products of lymphocytes from normal and syphilitic rabbits.

Authors:  S A Lukehart
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

3.  Experimental infection of man with rabbit-virulent Treponema paraluis-cuniculi.

Authors:  S Graves; J Downes
Journal:  Br J Vener Dis       Date:  1981-02

Review 4.  Cell-mediated immunity during syphilis.

Authors:  C S Pavis; J D Folds; J B Baseman
Journal:  Br J Vener Dis       Date:  1978-06

5.  Immunization of guinea pigs with recombinant TmpB antigen induces protection against challenge infection with Treponema pallidum Nichols.

Authors:  K Wicher; L M Schouls; V Wicher; J D Van Embden; S S Nakeeb
Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

6.  Depression of lymphocyte response to concanavalin A in rabbits infected with Treponema pallidum (Nichols strain).

Authors:  C S Pavia; J D Folds; J B Baseman
Journal:  Infect Immun       Date:  1976-07       Impact factor: 3.441

7.  Rate of clearance of virulent Treponema pallidum (Nichols) from the blood stream of normal, Mycobacterium bovis BCG-treated, and immune syphilitic rabbits.

Authors:  S Graves
Journal:  Infect Immun       Date:  1980-01       Impact factor: 3.441

8.  Nitroblue tetrazolium test in experimental syphilis.

Authors:  V Wicher; S Blakowski; K Wicher
Journal:  Br J Vener Dis       Date:  1977-10

9.  Inability of spleen cells from chancre-immune rabbits to confer immunity to challenge with Treponema pallidum.

Authors:  R E Baughn; D M Musher; C B Simmons
Journal:  Infect Immun       Date:  1977-09       Impact factor: 3.441

10.  Susceptibility of rabbits to Treponema pallidum after infection with Mycobacterium bovis.

Authors:  S Graves
Journal:  Br J Vener Dis       Date:  1979-12
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