Literature DB >> 17244561

Restoring function after spinal cord injury: promoting spontaneous regeneration with stem cells and activity-based therapies.

Visar Belegu1, Martin Oudega, Devin S Gary, John W McDonald.   

Abstract

Although neural regeneration is an active research field today, no current treatments can aid regeneration after spinal cord injury. This article reviews the feasibility of spinal cord repair and provides an overview of the range of strategies scientists are taking toward regeneration. The major focus of this article is the future role of stem cell transplantation and similar rehabilitative restorative approaches designed to optimize spontaneous regeneration by mobilizing endogenous stem cells and facilitating other cellular mechanisms of regeneration, such as axonal growth and myelination.

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Year:  2007        PMID： 17244561     DOI： 10.1016/j.nec.2006.10.012

Source DB:  PubMed          Journal:  Neurosurg Clin N Am        ISSN： 1042-3680            Impact factor:   2.509


  13 in total

1.  Tracking stem cell differentiation in the setting of automated optogenetic stimulation.

Authors:  Albrecht Stroh; Hsing-Chen Tsai; Li-Ping Wang; Feng Zhang; Jenny Kressel; Alexander Aravanis; Nandhini Santhanam; Karl Deisseroth; Arthur Konnerth; M Bret Schneider
Journal:  Stem Cells       Date:  2011-01       Impact factor: 6.277

2.  Effectiveness of intense, activity-based physical therapy for individuals with spinal cord injury in promoting motor and sensory recovery: is olfactory mucosa autograft a factor?

Authors:  Cathy A Larson; Paula M Dension
Journal:  J Spinal Cord Med       Date:  2013-01       Impact factor: 1.985

3.  Comparison of systemic and localized carrier-mediated delivery of methylprednisolone succinate for treatment of acute spinal cord injury.

Authors:  Maxim E Baltin; Diana E Sabirova; Elvira I Kiseleva; Marat I Kamalov; Timur I Abdullin; Natalia V Petrova; Nafis F Ahmetov; Oscar A Sachenkov; Tatiana V Baltina; Igor A Lavrov
Journal:  Exp Brain Res       Date:  2021-01-02       Impact factor: 1.972

4.  A Longitudinal Study of the Neurologic Safety of Acute Baclofen Use After Spinal Cord Injury.

Authors:  Jacquelyn J Cragg; Bobo Tong; Catherine R Jutzeler; Freda M Warner; Neil Cashman; Fred Geisler; John L K Kramer
Journal:  Neurotherapeutics       Date:  2019-07       Impact factor: 7.620

5.  Lower extremity functional electrical stimulation cycling promotes physical and functional recovery in chronic spinal cord injury.

Authors:  Cristina L Sadowsky; Edward R Hammond; Adam B Strohl; Paul K Commean; Sarah A Eby; Diane L Damiano; Jason R Wingert; Kyongtae T Bae; John W McDonald
Journal:  J Spinal Cord Med       Date:  2013-03-20       Impact factor: 1.985

6.  Promoting directional axon growth from neural progenitors grafted into the injured spinal cord.

Authors:  Joseph F Bonner; Armin Blesch; Birgit Neuhuber; Itzhak Fischer
Journal:  J Neurosci Res       Date:  2010-05-01       Impact factor: 4.164

Review 7.  The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration.

Authors:  Jessy John Alexander; Aileen Judith Anderson; Scott Robert Barnum; Beth Stevens; Andrea Joan Tenner
Journal:  J Neurochem       Date:  2008-10-24       Impact factor: 5.372

8.  Advances in Spinal Functional Magnetic Resonance Imaging in the Healthy and Injured Spinal Cords.

Authors:  Ann S Choe
Journal:  Curr Phys Med Rehabil Rep       Date:  2017-07-31

9.  Extensive neurological recovery from a complete spinal cord injury: a case report and hypothesis on the role of cortical plasticity.

Authors:  Ann S Choe; Visar Belegu; Shoko Yoshida; Suresh Joel; Cristina L Sadowsky; Seth A Smith; Peter C M van Zijl; James J Pekar; John W McDonald
Journal:  Front Hum Neurosci       Date:  2013-06-25       Impact factor: 3.169

10.  Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice.

Authors:  Yi-Fang Cui; Jin-Chong Xu; Gunnar Hargus; Igor Jakovcevski; Melitta Schachner; Christian Bernreuther
Journal:  PLoS One       Date:  2011-03-18       Impact factor: 3.240
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