| Literature DB >> 17244259 |
Chris Pickering1, Tiago Moreira, Sture Liljequist.
Abstract
In a previous report, we found that a 5-min. delay in alcohol access increases ethanol intake in rats trained to self-administer 5% ethanol. To assess the effects of this delay on the motivation to self-administer ethanol, Wistar rats were trained on a progressive ratio schedule of reinforcement and presented with the 5-min. delay. There was no change in break point (6 presses/delivery), active (125 presses/30 min.) or inactive (10 presses/30 min.) lever presses after the 5-min. delay compared to baseline. However, response cessation occurred 10 min. earlier in this delay session compared to baseline indicating that consumption was accelerated by delayed access to alcohol.Entities:
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Year: 2007 PMID: 17244259 DOI: 10.1111/j.1742-7843.2006.00002.x
Source DB: PubMed Journal: Basic Clin Pharmacol Toxicol ISSN: 1742-7835 Impact factor: 4.080