OBJECTIVE: The purpose of this study was to illustrate and review the MRI appearance of histologically proven cases of bone marrow necrosis (BMN) and to review the literature on this clinicopathologic entity with emphasis on its distinction from avascular necrosis (AVN) of bone. CONCLUSION: BMN is a rare clinicopathologic entity separate from AVN and has a distinctive MRI appearance. As MRI comes to play an increasingly important role in the evaluation of bone marrow disease, BMN is likely to be more frequently encountered. Awareness of BMN and its MRI appearance and appreciation of the frequent association between BMN and underlying malignancy may assist in the early diagnosis of BMN and initiate an intensive search for occult malignancy.
OBJECTIVE: The purpose of this study was to illustrate and review the MRI appearance of histologically proven cases of bone marrow necrosis (BMN) and to review the literature on this clinicopathologic entity with emphasis on its distinction from avascular necrosis (AVN) of bone. CONCLUSION: BMN is a rare clinicopathologic entity separate from AVN and has a distinctive MRI appearance. As MRI comes to play an increasingly important role in the evaluation of bone marrow disease, BMN is likely to be more frequently encountered. Awareness of BMN and its MRI appearance and appreciation of the frequent association between BMN and underlying malignancy may assist in the early diagnosis of BMN and initiate an intensive search for occult malignancy.
Authors: Ana I García; Ana Milinkovic; Xavier Tomás; José Rios; Iñaki Pérez; Sergi Vidal-Sicart; Jaume Pomés; Montserrat Del Amo; Josep Mallolas Journal: Skeletal Radiol Date: 2011-04-10 Impact factor: 2.199