Literature DB >> 17241843

Medication abortion employing routine sequential measurements of serum hCG and sonography only when indicated.

Wesley Clark1, Tanya Panton, Louisa Hann, Marji Gold.   

Abstract

OBJECTIVES: This study was designed to demonstrate the safety and efficacy of providing medication abortion in a primary care site without routine use of pre- and postprocedure transvaginal sonography.
METHODS: We performed a retrospective record review of 172 consecutive patients choosing medication abortion at our clinic. Our protocol used sonography only as needed for specific indications. All patients were intended to be followed up with serum human chorionic gonadotropin (hCG) testing pre- and posttreatment.
RESULTS: Of the 151 patients not lost to follow-up, 96 (63%) had pretreatment sonography according to protocol or physician preference and 55 did not. Ninety-nine percent (95/96) of those receiving initial sonography had a successful, and uneventful, medication abortion treatment, while 98.2% (54/55) of those not receiving an initial sonography did so. This difference was not statistically significant (.597 by one-sided Fisher's Exact Test). All 119 of the women who did not receive postabortion sonography aborted completely. Only 4 of the 91 women who had both pre- and postprocedure hCG measurements, all of whom aborted successfully, had follow-up-to-initial hCG ratios of greater than 0.2 (20%).
CONCLUSION: Using a clinical protocol that involves obtaining pre- and posttreatment serum hCG measurements, with sonograms only when indicated, has similar outcomes to a protocol that uses mandatory pre- and posttreatment sonograms.

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Year:  2006        PMID: 17241843     DOI: 10.1016/j.contraception.2006.08.001

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  4 in total

1.  First-trimester medical abortion practices in Canada: National survey.

Authors:  Edith R Guilbert; Althea S Hayden; Heidi E Jones; Katharine O'Connell White; E Steven Lichtenberg; Maureen Paul; Wendy V Norman
Journal:  Can Fam Physician       Date:  2016-04       Impact factor: 3.275

2.  Utility and Limitations of Human Chorionic Gonadotropin Levels for Remote Follow-up After Medical Management of Early Pregnancy Loss.

Authors:  Andrea H Roe; Alice Abernathy; Anne N Flynn; Arden McAllister; Nathanael C Koelper; Mary D Sammel; Courtney A Schreiber; Sarita Sonalkar
Journal:  Obstet Gynecol       Date:  2022-05-02       Impact factor: 7.623

3.  Comparing telemedicine to in-clinic medication abortions induced with mifepristone and misoprostol.

Authors:  Ellen R Wiebe; Mackenzie Campbell; Harani Ramasamy; Michaela Kelly
Journal:  Contracept X       Date:  2020-04-11

4.  Misoprostol Abortion: Ultrasonography versus Beta-hCG Testing for Verification of Effectiveness.

Authors:  Fariba Behnamfar; Mehrdad Mahdian; Fereshteh Rahimi; Mansoureh Samimi
Journal:  Pak J Med Sci       Date:  2013-11       Impact factor: 1.088

  4 in total

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