OBJECTIVE: The aim was to analyze and compare neurocognitive test profiles related to different levels of verbal learning performance among schizopsychotic patients and healthy volunteers. METHOD: A single-center patient cohort of 196 participants was compared with an equal-sized volunteer group to form three cognitive subgroups based on the shared verbal learning performance. RESULTS: 43.9% of the patients had normal learning ability. Despite this, all patients underperformed the volunteers on all subtests with the exception of working memory, and, for those with high learning ability, even verbal facility. All patients also presented equally poor visuomotor processing speed/efficacy. CONCLUSION: A global neurocognitive retardation of speed-related processing in schizophrenia is suggested.
OBJECTIVE: The aim was to analyze and compare neurocognitive test profiles related to different levels of verbal learning performance among schizopsychotic patients and healthy volunteers. METHOD: A single-center patient cohort of 196 participants was compared with an equal-sized volunteer group to form three cognitive subgroups based on the shared verbal learning performance. RESULTS: 43.9% of the patients had normal learning ability. Despite this, all patients underperformed the volunteers on all subtests with the exception of working memory, and, for those with high learning ability, even verbal facility. All patients also presented equally poor visuomotor processing speed/efficacy. CONCLUSION: A global neurocognitive retardation of speed-related processing in schizophrenia is suggested.
Authors: Yuliya Zaytseva; Iveta Fajnerová; Boris Dvořáček; Eva Bourama; Ilektra Stamou; Kateřina Šulcová; Jiří Motýl; Jiří Horáček; Mabel Rodriguez; Filip Španiel Journal: Front Psychol Date: 2018-07-03
Authors: Toby Pillinger; Maria Rogdaki; Robert A McCutcheon; Pamela Hathway; Alice Egerton; Oliver D Howes Journal: Psychopharmacology (Berl) Date: 2019-02-28 Impact factor: 4.530