Literature DB >> 17241760

Autologous fat transfer in reconstructive breast surgery: indications, technique and results.

M C Missana1, I Laurent, L Barreau, C Balleyguier.   

Abstract

AIMS: Reconstructive techniques using flaps to preserve the enveloping skin, and even the nipple areolar complex where there is no neoplastic infiltration, have led to vast improvements in the results of reconstructive breast surgery. To further improve the cosmetic outcome, we have applied the technique of autologous fat transfer or lipoinjection, which has proven very successful in cosmetic surgery, to reconstructive breast surgery, and to the treatment of certain cosmetic sequelae of conservative breast treatment. We report our findings.
METHODS: From September 2001 to September 2005, 74 autologous fat transfers were undertaken in 69 patients, with 5 patients receiving injections in both breasts, to improve the cosmetic appearance through resurfacing and to repair certain sequelae of conservative breast treatment. Pre- and postoperative imaging, including MRI, were undertaken to monitor the viability of the fat grafts and detect any suspicious lesions; no suspect lesions were detected either pre- or postoperatively.
RESULTS: We did not undertake overcorrection, which creates irregularities of surface or contour. Five cases of cytosteatonecrosis were reported among the 74 procedures. The mean follow-up period for the patients was 11.7 months, ranging from 1 month to 3.2 years. The panel judged improvement to be good to very good in 64 breasts (86.5%) and moderate in 10 breasts (13.5%) primarily due to lack of available adipose material for harvesting in these patients.
CONCLUSION: Autologous fat transfer is now a routine procedure in our clinic due to its simplicity, safety, and reproducibility. It is systematically proposed to all of our patients as the final, perfecting procedure of breast reconstruction, irrespective of the technique used for the initial reconstructive procedure, but also to repair certain conservative treatments.

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Year:  2007        PMID: 17241760     DOI: 10.1016/j.ejso.2006.12.002

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  32 in total

1.  Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification.

Authors:  Hong Youl Kim; Bok Ki Jung; Dae Hyun Lew; Dong Won Lee
Journal:  Arch Plast Surg       Date:  2014-11-03

Review 2.  Adipose-derived stem cells for clinical applications: a review.

Authors:  A Wilson; P E Butler; A M Seifalian
Journal:  Cell Prolif       Date:  2011-02       Impact factor: 6.831

3.  Autologous Fat Transplantation to the Reconstructed Breast Does not Hinder Assessment of Mammography and Ultrasound: A Cohort Study.

Authors:  Anna Lindegren; Marie Wickman Chantereau; Malin Bygdeson; Edward Azavedo; Inkeri Schultz
Journal:  World J Surg       Date:  2016-05       Impact factor: 3.352

4.  Fast and simple fat grafting of the breast.

Authors:  Rasmus Nygård Kristensen; Gudjon L Gunnarsson; Mikkel Børsen-Koch; Ashwin Reddy; Henrik Ømark; Jens Ahm Sørensen; Jørn Bo Thomsen
Journal:  Gland Surg       Date:  2015-12

5.  Adipose-derived stem cell (ASC)-enriched fat grafting: experiments using White rabbits and an automated cell processing apparatus.

Authors:  Natsuko Kakudo; Naoki Morimoto; Takeshi Ogawa; Masakatsu Hihara; Fangyuan Lai; Kenji Kusumoto
Journal:  Med Mol Morphol       Date:  2017-04-24       Impact factor: 2.309

Review 6.  Adipose Tissue-Derived Stem Cells in Regenerative Medicine.

Authors:  Laura Frese; Petra E Dijkman; Simon P Hoerstrup
Journal:  Transfus Med Hemother       Date:  2016-07-26       Impact factor: 3.747

Review 7.  The use of fat grafting and platelet-rich plasma for wound healing: A review of the current evidence.

Authors:  Oliver J Smith; Gavin Jell; Ash Mosahebi
Journal:  Int Wound J       Date:  2018-11-20       Impact factor: 3.315

8.  Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis.

Authors:  S B Bahrami; C Tolg; T Peart; C Symonette; M Veiseh; J U Umoh; D W Holdsworth; J B McCarthy; L G Luyt; M J Bissell; A Yazdani; E A Turley
Journal:  Integr Biol (Camb)       Date:  2017-02-20       Impact factor: 2.192

9.  Safety concern between autologous fat graft, mesenchymal stem cell and osteosarcoma recurrence.

Authors:  Pierre Perrot; Julie Rousseau; Anne-Laure Bouffaut; Françoise Rédini; Elisabeth Cassagnau; Frédéric Deschaseaux; Marie-Françoise Heymann; Dominique Heymann; Franck Duteille; Valérie Trichet; François Gouin
Journal:  PLoS One       Date:  2010-06-08       Impact factor: 3.240

10.  Does platelet-rich plasma enhance the survival of grafted fat? An update review.

Authors:  Rong Jin; Lu Zhang; Yu-Guang Zhang
Journal:  Int J Clin Exp Med       Date:  2013-04-12
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