| Literature DB >> 17240483 |
D Wendling1, C Prati, P Ornetti, E Toussirot, G Streit.
Abstract
INTRODUCTION: Anti TNF-alpha agents may represent a possibility of treatment in cases of refractory polymyositis. CASE REPORT: We report a case of polymyositis refractory to corticosteroids and immunosuppressive agents in whom adjunction of infliximab led to a mild and transient improvement, and a secondary improvement after discontinuation of the treatment. DISCUSSION: In the reported cases of polymyositis treated with infliximab or etanercept a short-term response was seen in 9 out of 11 cases. Adverse events of the treatment are mentioned, and should be taken into account in the decision of treatment.Entities:
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Year: 2007 PMID： 17240483 DOI： 10.1016/j.revmed.2006.12.001
Source DB: PubMed Journal: Rev Med Interne ISSN： 0248-8663 Impact factor: 0.728