| Literature DB >> 17240329 |
David M Wilson1, Mark P Mattson.
Abstract
Ataxia oculomotor apraxia-1 is a neurological disorder that arises from mutations in the gene encoding the protein aprataxin. A recent study demonstrates that aprataxin is critical for the processing of obstructive DNA termini, suggesting a broader role for DNA single-strand break repair in neurodegenerative disease.Entities:
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Year: 2007 PMID： 17240329 DOI： 10.1016/j.cub.2006.12.012
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834