OBJECTIVE: This study was undertaken to assess the long-term outcome of children born after a first-trimester measurement of nuchal translucency (NT) at the 99th percentile or greater during routine first-trimester screening in an unselected population. STUDY DESIGN: One hundred sixty-two infants were born alive. Clinical examination as well as a questionnaire to the parents (Ages and Stages Questionnaires [ASQ]) at the age of 2 years were obtained in 160 children. Our study population was compared with an external control group made of the 370 term control children. RESULTS: The prevalence of abnormal clinical pediatric examination and ASQ results at 2 years were not associated with NT thickness. Comparison with an external control group did not demonstrate an increased incidence of developmental delay. CONCLUSION: Parents should be informed that when the fetus is shown to be normal by ultrasound at 22-24 weeks of gestation the risk of adverse neonatal outcome or developmental delay in early childhood is not increased.
OBJECTIVE: This study was undertaken to assess the long-term outcome of children born after a first-trimester measurement of nuchal translucency (NT) at the 99th percentile or greater during routine first-trimester screening in an unselected population. STUDY DESIGN: One hundred sixty-two infants were born alive. Clinical examination as well as a questionnaire to the parents (Ages and Stages Questionnaires [ASQ]) at the age of 2 years were obtained in 160 children. Our study population was compared with an external control group made of the 370 term control children. RESULTS: The prevalence of abnormal clinical pediatric examination and ASQ results at 2 years were not associated with NT thickness. Comparison with an external control group did not demonstrate an increased incidence of developmental delay. CONCLUSION: Parents should be informed that when the fetus is shown to be normal by ultrasound at 22-24 weeks of gestation the risk of adverse neonatal outcome or developmental delay in early childhood is not increased.
Authors: P A Boyd; M Y Anthony; N Manning; C L Rodriguez; D G Wellesley; P Chamberlain Journal: Arch Dis Child Fetal Neonatal Ed Date: 1996-01 Impact factor: 5.747
Authors: B Larroque; G Bréart; M Kaminski; M Dehan; M André; A Burguet; H Grandjean; B Ledésert; C Lévêque; F Maillard; J Matis; J C Rozé; P Truffert Journal: Arch Dis Child Fetal Neonatal Ed Date: 2004-03 Impact factor: 5.747
Authors: R Buffin; A Fichez; E Decullier; A Roux; S Bin; D Combourieu; B Pastor-Diez; C Huissoud; J-C Picaud Journal: Ultrasound Obstet Gynecol Date: 2021-04-07 Impact factor: 7.299
Authors: Malgorzata I Srebniak; Merel C de Wit; Karin E M Diderich; Lutgarde C P Govaerts; Marieke Joosten; Maarten F C M Knapen; Marnix J Bos; Gerda A G Looye-Bruinsma; Mieke Koningen; Attie T J I Go; Robert Jan H Galjaard; Diane Van Opstal Journal: Mol Cytogenet Date: 2016-09-07 Impact factor: 2.009