Literature DB >> 17240140

Synthesis and structure evaluation of a novel cantharimide and its cytotoxicity on SK-Hep-1 hepatoma cells.

Stanton Hon Lung Kok1, Chung Hin Chui, Wing Sze Lam, Jien Chen, Fung Yi Lau, Raymond Siu Ming Wong, Gregory Yin Ming Cheng, Paul Bo San Lai, Thomas Wai Tong Leung, Michael Wing Yiu Yu, Johnny Cheuk On Tang, Albert Sun Chi Chan.   

Abstract

A remarkable control of the potency of cantharimide is described based on the electronic properties of functional group and it exhibits a relatively less toxic effect to the non-malignant hematological disorder bone marrow cells.

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Year:  2006        PMID: 17240140     DOI: 10.1016/j.bmcl.2006.12.039

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA.

Authors:  Zhaiyi Zhang; Olga Kelemen; Maria A van Santen; Sharon M Yelton; Alison E Wendlandt; Vitaliy M Sviripa; Mathieu Bollen; Monique Beullens; Henning Urlaub; Reinhard Lührmann; David S Watt; Stefan Stamm
Journal:  J Biol Chem       Date:  2011-01-10       Impact factor: 5.157

2.  Synthesis and biological evaluation of novel benzothiazole-2-thiol derivatives as potential anticancer agents.

Authors:  Xuan-Hong Shi; Zhao Wang; Yong Xia; Ting-Hong Ye; Mei Deng; You-Zhi Xu; Yu-Quan Wei; Luo-Ting Yu
Journal:  Molecules       Date:  2012-03-30       Impact factor: 4.411

  2 in total

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