Literature DB >> 17239872

A pilot study on the off-label use of valproic acid to treat adenomyosis.

Xishi Liu1, Sun-Wei Guo.   

Abstract

Following on the heels of the discovery that endometriosis is an epigenetic disease, we conducted a pilot study on the off-label use of valproic acid to treat adenomyosis. We found that by the end of the 3-month treatment, all three recruited patients reported complete disappearance of dysmenorrhea, with an average of one-third reduction in uterus size.

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Year:  2007        PMID: 17239872     DOI: 10.1016/j.fertnstert.2006.11.009

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  8 in total

1.  Adenomyosis: Mechanisms and Pathogenesis.

Authors:  Junyu Zhai; Silvia Vannuccini; Felice Petraglia; Linda C Giudice
Journal:  Semin Reprod Med       Date:  2020-10-08       Impact factor: 1.303

2.  The expression of histone deacetylase 1, but not other class I histone deacetylases, is significantly increased in endometriosis.

Authors:  Eleftherios P Samartzis; Aurelia Noske; Nicolas Samartzis; Daniel Fink; Patrick Imesch
Journal:  Reprod Sci       Date:  2013-05-20       Impact factor: 3.060

3.  Potential mechanisms of an antiadenomyosis chinese herbal formula shaoyao-gancao decoction in primary cell culture model.

Authors:  Yong-Ge Guan; Jin-Bin Liao; Kun-Yin Li; Yu-Cui Li; Yang Song; Jing Ling; Zi-Ren Su
Journal:  Evid Based Complement Alternat Med       Date:  2014-11-10       Impact factor: 2.629

4.  Anti-platelet therapy holds promises in treating adenomyosis: experimental evidence.

Authors:  Bo Zhu; Yumei Chen; Xiaolu Shen; Xishi Liu; Sun-Wei Guo
Journal:  Reprod Biol Endocrinol       Date:  2016-10-10       Impact factor: 5.211

5.  Leonurine Attenuates Hyperalgesia in Mice with Induced Adenomyosis.

Authors:  Jichan Nie; Xishi Liu
Journal:  Med Sci Monit       Date:  2017-04-08

Review 6.  Medical treatments for endometriosis-associated pelvic pain.

Authors:  Gabriella Zito; Stefania Luppi; Elena Giolo; Monica Martinelli; Irene Venturin; Giovanni Di Lorenzo; Giuseppe Ricci
Journal:  Biomed Res Int       Date:  2014-08-07       Impact factor: 3.411

Review 7.  The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights.

Authors:  Antonio Simone Laganà; Simone Garzon; Martin Götte; Paola Viganò; Massimo Franchi; Fabio Ghezzi; Dan C Martin
Journal:  Int J Mol Sci       Date:  2019-11-10       Impact factor: 5.923

Review 8.  Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis.

Authors:  Sun-Wei Guo
Journal:  Reprod Med Biol       Date:  2018-08-16
  8 in total

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