| Literature DB >> 17239868 |
Navid Esfandiari1, Tommaso Falcone, Jeffrey M Goldberg, Ashok Agarwal, Rakesh K Sharma.
Abstract
We investigated the effect of antibodies to heat-shock proteins 60 and 70 on development, reactive oxygen species production, and incidence of apoptosis in preimplantation mouse embryos. Supplementation of culture media with antibodies to heat-shock proteins 60 and 70 resulted in significantly lower blastocyst development, hatching rate, reduced total cell number, and trophectoderm cell number, and increased the incidence of apoptosis in blastocysts compared to the control group.Entities:
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Year: 2007 PMID： 17239868 DOI： 10.1016/j.fertnstert.2006.07.1536
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329