Literature DB >> 17238416

Mining cross-terminology links in the UMLS.

Chintan O Patel1, James J Cimino.   

Abstract

OBJECTIVE: To explore link mining approaches over transitive relationship paths in the Unified Medical Language System (UMLS). The goal is to classify relevant and 'interesting' cross-terminology links/paths for integration of Electronic Health Records (EHRs) and information resources.
METHODS: We present approaches for using the link semantics as learning features, sampling the UMLS to create training examples, and ranking the classified links. We use the clinical query and MEDLINE pairs in the OHSUMED dataset to extract 'gold-links' between SNOMED-CT and MeSH respectively, and compare them against corresponding two-step transitive links generated from the UMLS.
RESULTS: a). 75.7% increase in reachable MeSH concepts with two-step links as compared to direct one-step links b). 94.08% recall after link classification.
CONCLUSION: Using link mining with the UMLS is a promising approach for inter-terminology translation; further research is needed to handle the exponential link growth.

Mesh:

Year:  2006        PMID: 17238416      PMCID: PMC1839716     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  7 in total

1.  Comparing associative relationships among equivalent concepts across ontologies.

Authors:  Songmao Zhang; Olivier Bodenreider
Journal:  Stud Health Technol Inform       Date:  2004

2.  The MEDLINE Button.

Authors:  J J Cimino; S B Johnson; A Aguirre; N Roderer; P D Clayton
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1992

3.  Beyond synonymy: exploiting the UMLS semantics in mapping vocabularies.

Authors:  O Bodenreider; S J Nelson; W T Hole; H F Chang
Journal:  Proc AMIA Symp       Date:  1998

4.  Supporting infobuttons with terminological knowledge.

Authors:  J J Cimino; G Elhanan; Q Zeng
Journal:  Proc AMIA Annu Fall Symp       Date:  1997

5.  The Unified Medical Language System.

Authors:  D A Lindberg; B L Humphreys; A T McCray
Journal:  Methods Inf Med       Date:  1993-08       Impact factor: 2.176

Review 6.  Accessing heterogeneous sources of evidence to answer clinical questions.

Authors:  E A Mendonça; J J Cimino; S B Johnson; Y H Seol
Journal:  J Biomed Inform       Date:  2001-04       Impact factor: 6.317

7.  KnowledgeLink: impact of context-sensitive information retrieval on clinicians' information needs.

Authors:  Saverio M Maviglia; Catherine S Yoon; David W Bates; Gilad Kuperman
Journal:  J Am Med Inform Assoc       Date:  2005-10-12       Impact factor: 4.497

  7 in total
  3 in total

1.  Enabling integrative genomic analysis of high-impact human diseases through text mining.

Authors:  Joel Dudley; Atul J Butte
Journal:  Pac Symp Biocomput       Date:  2008

2.  Using semantic and structural properties of the Unified Medical Language System to discover potential terminological relationships.

Authors:  Chintan O Patel; James J Cimino
Journal:  J Am Med Inform Assoc       Date:  2009-03-04       Impact factor: 4.497

Review 3.  Can literature analysis identify innovation drivers in drug discovery?

Authors:  Pankaj Agarwal; David B Searls
Journal:  Nat Rev Drug Discov       Date:  2009-11       Impact factor: 84.694

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.