BACKGROUND: Depression is an important predictor of post therapy quality of life (QOL) in head and neck (H&N) cancer patients. In addition, depression rates may vary among cultures. OBJECTIVE: As part of a larger cross cultural study on post therapy QOL differences in H&N cancer patients, the goal of this project was to translate a well-validated English language depression scale into Swahili, and then validate this scale in Kenyan H&N cancer patients. METHODS, SETTINGS AND SUBJECTS: In Part 1 of the study, we translated the Patient Health Questionnaire-9 (PHQ-9) into Swahili, adhering to established International Quality of Life Association (IQOLA) guidelines. In Part 2, we psychometrically validated the newly translated scale using a prospective study of 48 patients at the Kenyatta National Hospital ENT clinic in Nairobi, Kenya. RESULTS: The Swahili PHQ-9 had good test retest reliability (Intraclass correlation coefficient, 0.71) and internal consistency (Cronbach's alpha = 0.80). It also had good construct validity, as scores correlated strongly with TNM stage (Chi square = 123, p < 0.05), and with the compositeand global scores of an H&N cancer specific QOL scale (UW-QOL, r = -0.87, p < 0.05). CONCLUSION: The Swahili version of the PHQ-9 is a reliable scale in Kenyan H&N cancer patients, and is a valuable tool in screening for and monitoring of depression as a function of QOL in this population.
BACKGROUND:Depression is an important predictor of post therapy quality of life (QOL) in head and neck (H&N) cancerpatients. In addition, depression rates may vary among cultures. OBJECTIVE: As part of a larger cross cultural study on post therapy QOL differences in H&N cancerpatients, the goal of this project was to translate a well-validated English language depression scale into Swahili, and then validate this scale in Kenyan H&N cancerpatients. METHODS, SETTINGS AND SUBJECTS: In Part 1 of the study, we translated the Patient Health Questionnaire-9 (PHQ-9) into Swahili, adhering to established International Quality of Life Association (IQOLA) guidelines. In Part 2, we psychometrically validated the newly translated scale using a prospective study of 48 patients at the Kenyatta National Hospital ENT clinic in Nairobi, Kenya. RESULTS: The Swahili PHQ-9 had good test retest reliability (Intraclass correlation coefficient, 0.71) and internal consistency (Cronbach's alpha = 0.80). It also had good construct validity, as scores correlated strongly with TNM stage (Chi square = 123, p < 0.05), and with the compositeand global scores of an H&N cancer specific QOL scale (UW-QOL, r = -0.87, p < 0.05). CONCLUSION: The Swahili version of the PHQ-9 is a reliable scale in Kenyan H&N cancerpatients, and is a valuable tool in screening for and monitoring of depression as a function of QOL in this population.
Authors: Jennifer A Downs; Charles Mguta; Godfrey M Kaatano; Katrina B Mitchell; Heejung Bang; Harusha Simplice; Samuel E Kalluvya; John M Changalucha; Warren D Johnson; Daniel W Fitzgerald Journal: Am J Trop Med Hyg Date: 2011-03 Impact factor: 2.345
Authors: Linda G Marc; Whitney R Henderson; Astrid Desrosiers; Marcia A Testa; Samuel E Jean; Eniko Edit Akom Journal: J Gen Intern Med Date: 2014-08-05 Impact factor: 5.128
Authors: Kate S Wilson; George Wanje; Linnet Masese; Jane M Simoni; Juma Shafi; Lucy Adala; Julie Overbaugh; Walter Jaoko; Barbra A Richardson; Raymond S McClelland Journal: J Acquir Immune Defic Syndr Date: 2018-07-01 Impact factor: 3.731
Authors: Brian W Pence; Bradley N Gaynes; Julius Atashili; Julie K O'Donnell; Gladys Tayong; Dmitry Kats; Rachel Whetten; Kathryn Whetten; Alfred K Njamnshi; Peter M Ndumbe Journal: J Affect Disord Date: 2012-07-27 Impact factor: 4.839