Literature DB >> 17235598

Getting ready for the manned mission to Mars: the astronauts' risk from space radiation.

Christine E Hellweg1, Christa Baumstark-Khan.   

Abstract

Space programmes are shifting towards planetary exploration and, in particular, towards missions by human beings to the Moon and to Mars. Radiation is considered to be one of the major hazards for personnel in space and has emerged as the most critical issue to be resolved for long-term missions both orbital and interplanetary. The two cosmic sources of radiation that could impact a mission outside the Earth's magnetic field are solar particle events (SPE) and galactic cosmic rays (GCR). Exposure to the types of ionizing radiation encountered during space travel may cause a number of health-related problems, but the primary concern is related to the increased risk of cancer induction in astronauts. Predictions of cancer risk and acceptable radiation exposure in space are extrapolated from minimal data and are subject to many uncertainties. The paper describes present-day estimates of equivalent doses from GCR and solar cosmic radiation behind various shields and radiation risks for astronauts on a mission to Mars.

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Year:  2007        PMID: 17235598     DOI: 10.1007/s00114-006-0204-0

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  61 in total

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Journal:  Adv Space Res       Date:  1994-10       Impact factor: 2.152

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Journal:  Adv Space Res       Date:  1994-10       Impact factor: 2.152

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Authors:  Antone L Brooks
Journal:  Health Phys       Date:  2003-07       Impact factor: 1.316

4.  Interplanetary crew exposure estimates for galactic cosmic rays.

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Journal:  Radiat Res       Date:  1992-01       Impact factor: 2.841

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Authors:  G I Reeves; E J Ainsworth
Journal:  Radiat Res       Date:  1995-05       Impact factor: 2.841

6.  X-ray-induced DNA double-strand breaks as lethal lesions in diploid human fibroblasts compared to Chinese hamster ovary cells.

Authors:  C Baumstark-Khan
Journal:  Int J Radiat Biol       Date:  1993-03       Impact factor: 2.694

7.  Biological monitoring of radiation exposure.

Authors:  G Horneck
Journal:  Adv Space Res       Date:  1998       Impact factor: 2.152

8.  Non-subjective cataract analysis and its application in space radiation risk assessment.

Authors:  B Wu; C Medvedovsky; B V Worgul
Journal:  Adv Space Res       Date:  1994       Impact factor: 2.152

9.  Nuclear responses to protein kinase C signal transduction are sensitive to gravity changes.

Authors:  R P de Groot; P J Rijken; J den Hertog; J Boonstra; A J Verkleij; S W de Laat; W Kruijer
Journal:  Exp Cell Res       Date:  1991-11       Impact factor: 3.905

10.  Modeled microgravity-induced protein kinase C isoform expression in human lymphocytes.

Authors:  A Sundaresan; D Risin; N R Pellis
Journal:  J Appl Physiol (1985)       Date:  2004-02-13
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  50 in total

1.  Effects of Solar Particle Event-Like Proton Radiation and/or Simulated Microgravity on Circulating Mouse Blood Cells.

Authors:  Ana L Romero-Weaver; Liyong Lin; Alejandro Carabe-Fernandez; Ann R Kennedy
Journal:  Gravit Space Res       Date:  2014-08

2.  Orally Administered Fructose Increases the Numbers of Peripheral Lymphocytes Reduced by Exposure of Mice to Gamma or SPE-like Proton Radiation.

Authors:  A L Romero-Weaver; J Ni; L Lin; A R Kennedy
Journal:  Life Sci Space Res (Amst)       Date:  2014-07

3.  Imaging in space exploration.

Authors:  M Castillo
Journal:  AJNR Am J Neuroradiol       Date:  2011-12-15       Impact factor: 3.825

4.  Effects of proton radiation dose, dose rate and dose fractionation on hematopoietic cells in mice.

Authors:  J H Ware; J Sanzari; S Avery; C Sayers; G Krigsfeld; M Nuth; X S Wan; A Rusek; A R Kennedy
Journal:  Radiat Res       Date:  2010-09       Impact factor: 2.841

Review 5.  Space radiation and cardiovascular disease risk.

Authors:  Marjan Boerma; Gregory A Nelson; Vijayalakshmi Sridharan; Xiao-Wen Mao; Igor Koturbash; Martin Hauer-Jensen
Journal:  World J Cardiol       Date:  2015-12-26

6.  Different Sequences of Fractionated Low-Dose Proton and Single Iron-Radiation-Induced Divergent Biological Responses in the Heart.

Authors:  Sharath P Sasi; Xinhua Yan; Marian Zuriaga-Herrero; Hannah Gee; Juyong Lee; Raman Mehrzad; Jin Song; Jillian Onufrak; James Morgan; Heiko Enderling; Kenneth Walsh; Raj Kishore; David A Goukassian
Journal:  Radiat Res       Date:  2017-06-14       Impact factor: 2.841

7.  Mechanism of hypocoagulability in proton-irradiated ferrets.

Authors:  Gabriel S Krigsfeld; Alexandria R Savage; Jenine K Sanzari; Andrew J Wroe; Daila S Gridley; Ann R Kennedy
Journal:  Int J Radiat Biol       Date:  2013-06-10       Impact factor: 2.694

Review 8.  Maximizing information from space data resources: a case for expanding integration across research disciplines.

Authors:  Nandu Goswami; Jerry J Batzel; Gilles Clément; T Peter Stein; Alan R Hargens; M Keith Sharp; Andrew P Blaber; Peter G Roma; Helmut G Hinghofer-Szalkay
Journal:  Eur J Appl Physiol       Date:  2012-10-17       Impact factor: 3.078

9.  Dermatopathology effects of simulated solar particle event radiation exposure in the porcine model.

Authors:  Jenine K Sanzari; Eric S Diffenderfer; Sarah Hagan; Paul C Billings; Daila S Gridley; John T Seykora; Ann R Kennedy; Keith A Cengel
Journal:  Life Sci Space Res (Amst)       Date:  2015-06-18

10.  Embryonic development and skeletogenic gene expression affected by X-rays in the Mediterranean sea urchin Paracentrotus lividus.

Authors:  Valeria Matranga; Francesca Zito; Caterina Costa; Rosa Bonaventura; Salvatore Giarrusso; Filippo Celi
Journal:  Ecotoxicology       Date:  2009-11-27       Impact factor: 2.823

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