Literature DB >> 17234878

Modelling of municipal mortality due to haematological neoplasias in Spain.

Rebeca Ramis Prieto1, Javier García-Pérez, Marina Pollán, Nuria Aragonés, Beatriz Pérez-Gómez, Gonzalo López-Abente.   

Abstract

OBJECTIVES: To study the geographical pattern of mortality caused by haematological tumours in Spain at the municipal level using three Bayesian models and to compare their goodness of fit.
METHODS: The fitted Bayesian hierarchical models were: (1) the Besag York and Molliè (BYM) model; (2) a model based on zero-inflated Poisson (ZIP) distribution, which allowed a large number of event-free areas; and (3) a mixture of distributions that enabled discontinuities (jumps in the pattern) to be modelled. The three models allow smoothed relative risk maps to be obtained for the all countries. The goodness of fit was evaluated using the deviance information criteria.
RESULTS: The three models yielded similar results. The ZIP model plotted a pattern almost identical with the BYM model. The goodness-of-fit criteria indicate that the mixture model is the one that best fits our data. Haematological tumours display a geographical pattern that could be partly explained by environmental determinants, as many of the highest-risk towns are located in heavily industrialised areas.
CONCLUSIONS: The choice of one or another model has scant practical consequences. The pattern of distribution supports the hypothesis that differences in lifestyles, air/industrial pollution and migratory phenomena may determine the pattern of urban mortality due to these tumours.

Entities:  

Mesh:

Year:  2007        PMID: 17234878      PMCID: PMC2465634          DOI: 10.1136/jech.2005.041491

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN: 0143-005X            Impact factor:   3.710


  14 in total

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  10 in total

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