OBJECTIVE: We assessed the effects of an intervention aimed at increasing the consumption of fruits and vegetables on plasma folate and homocysteine concentrations. METHODS:Seventy-one healthy non-smoking women (mean +/- SD 41 +/- 4 y of age) were randomized to an intervention or a control group. Participants in the intervention group (n = 36) received weekly packets containing fruits and vegetables free of charge and were asked to consume a daily amount of >or=200 g of vegetables and two pieces of fruit (the Dutch recommended intake level) over a period of 1 mo. Control subjects did not receive any intervention. RESULTS: Compared with the control group, reported fruit and vegetable intakes in the intervention group increased by 133 g/d (95% confidence interval [CI] 87-179, P < 0.001) for fruits and juice and 64 g/d (95% CI 37-91, P < 0.001) for vegetables and estimated folate intake from fruits and vegetables increased by 40 microg/d (95% CI 22-58, P < 0.001). However, no effect was observed on plasma folate concentrations (intervention effect 0.3 nmol/L, 95% CI -1.8 to 2.8, P = 0.77) or homocysteine concentrations (intervention effect 0.26 micromol/L, 95% CI -0.34 to 0.87, P = 0.39). CONCLUSION: The results suggest that 4 wk of increased fruit and vegetable consumption to the recommended amounts may be insufficient to change plasma folate and homocysteine concentrations.
RCT Entities:
OBJECTIVE: We assessed the effects of an intervention aimed at increasing the consumption of fruits and vegetables on plasma folate and homocysteine concentrations. METHODS: Seventy-one healthy non-smoking women (mean +/- SD 41 +/- 4 y of age) were randomized to an intervention or a control group. Participants in the intervention group (n = 36) received weekly packets containing fruits and vegetables free of charge and were asked to consume a daily amount of >or=200 g of vegetables and two pieces of fruit (the Dutch recommended intake level) over a period of 1 mo. Control subjects did not receive any intervention. RESULTS: Compared with the control group, reported fruit and vegetable intakes in the intervention group increased by 133 g/d (95% confidence interval [CI] 87-179, P < 0.001) for fruits and juice and 64 g/d (95% CI 37-91, P < 0.001) for vegetables and estimated folate intake from fruits and vegetables increased by 40 microg/d (95% CI 22-58, P < 0.001). However, no effect was observed on plasma folate concentrations (intervention effect 0.3 nmol/L, 95% CI -1.8 to 2.8, P = 0.77) or homocysteine concentrations (intervention effect 0.26 micromol/L, 95% CI -0.34 to 0.87, P = 0.39). CONCLUSION: The results suggest that 4 wk of increased fruit and vegetable consumption to the recommended amounts may be insufficient to change plasma folate and homocysteine concentrations.
Authors: Jéssica Vanessa de Carvalho Lisboa; Marina Ramalho Ribeiro; Rafaella Cristhine Pordeus Luna; Raquel Patrícia Ataíde Lima; Rayner Anderson Ferreira do Nascimento; Mussara Gomes Cavalcante Alves Monteiro; Keylha Querino de Farias Lima; Carla Patrícia Novaes Dos Santos Fechine; Naila Francis Paulo de Oliveira; Darlene Camati Persuhn; Robson Cavalcante Veras; Maria da Conceição Rodrigues Gonçalves; Flávia Emília Leite de Lima Ferreira; Roberto Teixeira Lima; Alexandre Sérgio da Silva; Alcides da Silva Diniz; Aléssio Tony Cavalcanti de Almeida; Ronei Marcos de Moraes; Eliseu Verly Junior; Maria José de Carvalho Costa Journal: Nutrients Date: 2020-01-30 Impact factor: 5.717
Authors: Susan J Duthie; Garry G Duthie; Wendy R Russell; Janet A M Kyle; Jennie I Macdiarmid; Vanessa Rungapamestry; Sylvia Stephen; Cristina Megias-Baeza; Joanna J Kaniewska; Lindsey Shaw; Lesley Milne; David Bremner; Karen Ross; Philip Morrice; Lynn P Pirie; Graham Horgan; Charles S Bestwick Journal: Eur J Nutr Date: 2017-05-30 Impact factor: 5.614