| Literature DB >> 17234410 |
Lily Abbott1, Patrick Betschmann, Andrew Burchat, David J Calderwood, Heather Davis, Peter Hrnciar, Gavin C Hirst, Biqin Li, Michael Morytko, Kelly Mullen, Bryant Yang.
Abstract
We describe the identification, SAR, and in vivo pharmacology of a new series of Src-family selective Lck inhibitors. These thienopyridines were designed based on a desire to access the unique residues in the extended hinge region of Lck.Entities:
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Year: 2006 PMID： 17234410 DOI： 10.1016/j.bmcl.2006.12.035
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823