Literature DB >> 17234139

The genetic and environmental basis of hepatocellular carcinoma.

Paraskevi A Farazi1, Ronald A DePinho.   

Abstract

Liver cancer is among the most common malignancies, impacting significantly across all societies worldwide. The lethal impact of this prevalent cancer is unlikely to change considerably in the near future due to a limited understanding of disease pathogenesis on the molecular, cellular, and environmental levels and how current knowledge might be converted into new preventive, therapeutic and diagnostic approaches. This article highlights the current challenges and opportunities in this critical area of unmet need.

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Year:  2006        PMID: 17234139

Source DB:  PubMed          Journal:  Discov Med        ISSN: 1539-6509            Impact factor:   2.970


  12 in total

Review 1.  Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges.

Authors:  Yujin Hoshida; Bryan C Fuchs; Kenneth K Tanabe
Journal:  Curr Cancer Drug Targets       Date:  2012-11-01       Impact factor: 3.428

2.  Elevated Src expression associated with hepatocellular carcinoma metastasis in northern Chinese patients.

Authors:  Ran Zhao; Yiqi Wu; Tianzhen Wang; Yuhua Zhang; Dan Kong; Lei Zhang; Xiaobo Li; Guangyu Wang; Yinji Jin; Xiaoming Jin; Fengmin Zhang
Journal:  Oncol Lett       Date:  2015-09-16       Impact factor: 2.967

3.  TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer.

Authors:  Ji Yeon Baek; Shelli M Morris; Jean Campbell; Nelson Fausto; Matthew M Yeh; William M Grady
Journal:  Int J Cancer       Date:  2010-09-01       Impact factor: 7.396

4.  Reduced expression of ASS is closely related to clinicopathological features and post-resectional survival of hepatocellular carcinoma.

Authors:  Hua Yang; Ming Lin; Fu Xia Xiong; Yu Yang; Xiu Nie; Rou Li Zhou
Journal:  Oncol Lett       Date:  2010-01-01       Impact factor: 2.967

5.  How cancer shapes evolution, and how evolution shapes cancer.

Authors:  Matias Casás-Selves; James Degregori
Journal:  Evolution (N Y)       Date:  2011-12

Review 6.  Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis.

Authors:  Wen-Lung Ma; Hsueh-Chou Lai; Shuyuan Yeh; Xiujun Cai; Chawnshang Chang
Journal:  Endocr Relat Cancer       Date:  2014-05-06       Impact factor: 5.678

7.  Water-Soluble Total Flavonoids Isolated from Isodon lophanthoides var. gerardianus (Benth.) H. Hara Promote Hepatocellular Carcinoma Sensitivity to 5-Fluorouracil.

Authors:  Chuan-Ping Feng; Hai-Xia Ding; Ying-Xin Liu; Qing-Feng Di; Yan Liu; Jian Liang; Guang-Xi Liu
Journal:  Evid Based Complement Alternat Med       Date:  2021-07-17       Impact factor: 2.629

8.  Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.

Authors:  Alex Y Chang; Miao Wang
Journal:  BMC Cancer       Date:  2013-05-30       Impact factor: 4.430

9.  The associated ion between the VDR gene polymorphisms and susceptibility to hepatocellular carcinoma and the clinicopathological features in subjects infected with HBV.

Authors:  Xing Yao; Huazong Zeng; Guolei Zhang; Weimin Zhou; Qiang Yan; Licheng Dai; Xiang Wang
Journal:  Biomed Res Int       Date:  2013-03-23       Impact factor: 3.411

10.  Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion.

Authors:  Murat Cokakli; Esra Erdal; Deniz Nart; Funda Yilmaz; Ozgul Sagol; Murat Kilic; Sedat Karademir; Nese Atabey
Journal:  BMC Cancer       Date:  2009-02-24       Impact factor: 4.430

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