| Literature DB >> 17233821 |
Luca Arcaini1, Marco Paulli, Sara Burcheri, Andrea Rossi, Michele Spina, Francesco Passamonti, Marco Lucioni, Teresio Motta, Vincenzo Canzonieri, Mauro Montanari, Emanuela Bonoldi, Andrea Gallamini, Lilj Uziel, Monica Crugnola, Antonio Ramponi, Francesca Montanari, Cristiana Pascutto, Enrica Morra, Mario Lazzarino.
Abstract
This study defined the clinical features and assessed the prognosis of 47 patients (17 males, 30 females, median age 63 years) with primary nodal marginal zone B-cell lymphoma. Forty-five per cent had stage IV disease. Hepatitis C virus serology was positive in 24%. According to the Follicular Lymphoma International Prognostic Index (FLIPI), 33% were classified as low-risk, 34% as intermediate-risk, and 33% as high-risk. The 5-year overall survival (OS) was 69%. In univariate analysis worse OS was associated with: FLIPI (P = 0.02), age > 60 years (P = 0.05) and raised lactate dehydrogenase (P = 0.05). In multivariate analysis, only FLIPI predicted a worse OS (P = 0.02).Entities:
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Year: 2007 PMID： 17233821 DOI： 10.1111/j.1365-2141.2006.06437.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998