Literature DB >> 1723154

Study of regional cerebral blood flow in experimental head injury: changes following cerebral contusion and during spreading depression.

Y Ozawa1, T Nakamura, K Sunami, M Kubota, C Ito, H Murai, A Yamaura, H Makino.   

Abstract

Changes in regional cerebral blood flow (rCBF) following fluid-percussion brain injury (cerebral contusion) were studied in rats using the autoradiographic method. The direct current potential was monitored to identify spreading depression (SD). The rCBF was measured during SD and 2, 4, and 24 hours after injury. rCBF was almost nil in the contused area and decreased considerably in the cortices of the injured side for 4 hours after insult, then recovered by 24 hours. Focal relative rCBF increase occurred in the parietal cortex during SD, and was probably hyperperfusion due to SD. However, the rCBF did not increase over the sham-operated control. The injury probably caused hypoperfusion within 4 hours of insult and abolished the vascular response to SD.

Entities:  

Mesh：

Year:  1991        PMID： 1723154     DOI： 10.2176/nmc.31.685

Source DB:  PubMed          Journal:  Neurol Med Chir (Tokyo)        ISSN： 0470-8105            Impact factor:   1.742


  8 in total

Review 1.  Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury.

Authors:  Martin Lauritzen; Jens Peter Dreier; Martin Fabricius; Jed A Hartings; Rudolf Graf; Anthony John Strong
Journal:  J Cereb Blood Flow Metab       Date:  2010-11-03       Impact factor: 6.200

2.  Increased incidence and impact of nonconvulsive and convulsive seizures after traumatic brain injury as detected by continuous electroencephalographic monitoring.

Authors:  P M Vespa; M R Nuwer; V Nenov; E Ronne-Engstrom; D A Hovda; M Bergsneider; D F Kelly; N A Martin; D P Becker
Journal:  J Neurosurg       Date:  1999-11       Impact factor: 5.115

Review 3.  The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.

Authors:  Jed A Hartings; C William Shuttleworth; Sergei A Kirov; Cenk Ayata; Jason M Hinzman; Brandon Foreman; R David Andrew; Martyn G Boutelle; K C Brennan; Andrew P Carlson; Markus A Dahlem; Christoph Drenckhahn; Christian Dohmen; Martin Fabricius; Eszter Farkas; Delphine Feuerstein; Rudolf Graf; Raimund Helbok; Martin Lauritzen; Sebastian Major; Ana I Oliveira-Ferreira; Frank Richter; Eric S Rosenthal; Oliver W Sakowitz; Renán Sánchez-Porras; Edgar Santos; Michael Schöll; Anthony J Strong; Anja Urbach; M Brandon Westover; Maren Kl Winkler; Otto W Witte; Johannes Woitzik; Jens P Dreier
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

4.  Distinct spatiotemporal patterns of spreading depolarizations during early infarct evolution: evidence from real-time imaging.

Authors:  Tetsuya Kumagai; Maureen Walberer; Hajime Nakamura; Heike Endepols; Michael Sué; Stefan Vollmar; Sasan Adib; Günter Mies; Toshiki Yoshimine; Michael Schroeter; Rudolf Graf
Journal:  J Cereb Blood Flow Metab       Date:  2010-08-11       Impact factor: 6.200

Review 5.  Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications.

Authors:  Peter Toth; Nikolett Szarka; Eszter Farkas; Erzsebet Ezer; Endre Czeiter; Krisztina Amrein; Zoltan Ungvari; Jed A Hartings; Andras Buki; Akos Koller
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-09-09       Impact factor: 4.733

6.  Evolution of neuronal and astroglial disruption in the peri-contusional cortex of mice revealed by in vivo two-photon imaging.

Authors:  Jeremy Sword; Tadashi Masuda; Deborah Croom; Sergei A Kirov
Journal:  Brain       Date:  2013-03-06       Impact factor: 13.501

7.  Real-time optical diagnosis of the rat brain exposed to a laser-induced shock wave: observation of spreading depolarization, vasoconstriction and hypoxemia-oligemia.

Authors:  Shunichi Sato; Satoko Kawauchi; Wataru Okuda; Izumi Nishidate; Hiroshi Nawashiro; Gentaro Tsumatori
Journal:  PLoS One       Date:  2014-01-08       Impact factor: 3.240

8.  CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury.

Authors:  Nicole A Terpollili; Reinhard Dolp; Kai Waehner; Susanne M Schwarzmaier; Elisabeth Rumbler; Boyan Todorov; Michel D Ferrari; Arn M J M van den Maagdenberg; Nikolaus Plesnila
Journal:  Elife       Date:  2022-03-03       Impact factor: 8.140
  8 in total

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