Literature DB >> 1722983

Voltage-sensitive Na+ channels: motifs, modes and modulation.

M Stephan1, W S Agnew.   

Abstract

Much recent progress has been made in understanding the structural organization and functional properties of voltage-dependent Na+ channels, in particular in the areas of activation, ion conductance, and inactivation. At the same time, however, electrophysiological studies have revealed new, more complex functional properties in the form of at least two gating modes and the existence of as yet unidentified modulatory factors.

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Year:  1991        PMID： 1722983     DOI： 10.1016/0955-0674(91)90041-v

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  6 in total

1.  Constraints imposed by protease accessibility on the trans-membrane and surface topography of the colicin E1 ion channel.

Authors:  Y L Zhang; W A Cramer
Journal:  Protein Sci       Date:  1992-12       Impact factor: 6.725

2.  Hydrophobic free energy eigenfunctions of pore, channel, and transporter proteins contain beta-burst patterns.

Authors:  K A Selz; A J Mandell; M F Shlesinger
Journal:  Biophys J       Date:  1998-11       Impact factor: 4.033

3.  Inactivation of single cardiac Na+ channels in three different gating modes.

Authors:  T Böhle; M Steinbis; C Biskup; R Koopmann; K Benndorf
Journal:  Biophys J       Date:  1998-10       Impact factor: 4.033

4.  Recombinant interleukin-2 acts like a class I antiarrhythmic drug on human cardiac sodium channels.

Authors:  T Proebstle; M Mitrovics; M Schneider; V Hombach; R Rüdel
Journal:  Pflugers Arch       Date:  1995-02       Impact factor: 3.657

5.  The microI skeletal muscle sodium channel: mutation E403Q eliminates sensitivity to tetrodotoxin but not to mu-conotoxins GIIIA and GIIIB.

Authors:  M M Stephan; J F Potts; W S Agnew
Journal:  J Membr Biol       Date:  1994-01       Impact factor: 1.843

6.  The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells.

Authors:  D D Ginty; G R Fanger; J A Wagner; R A Maue
Journal:  J Cell Biol       Date:  1992-03       Impact factor: 10.539
  6 in total

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