Literature DB >> 17229804

Confident complete excision of lid-margin BCCs using a marginal strip: an alternative to Mohs' surgery.

Narendra Dhingra1, Adam Gajdasty, Jim W Neal, Achyut N Mukherjee, Carol M Lane.   

Abstract

AIMS: To report a new technique of tissue preparation, using a marginal strip, after the excision of eyelid basal cell carcinomas (BCCs) and to report the long-term results of BCCs excised using this technique.
METHOD: After the excision of eyelid BCC with a safety margin of 4 mm, a 1 mm strip was excised along the whole perimeter from the margin of the freshly excised specimen. This marginal strip had intact conjunctival mucosa along one edge and skin along the other. The marginal strip and the central tumour mass were then fixed immediately in formal saline and subjected to conventional histopathology.
RESULTS: Of the 61 patients who completed a 5 years follow-up, the results of 28 eye-lid BCCs that were within 4 mm of the lid margin are reported. The marginal strip was clear in 22 specimens and had the presence of residual tumour in its margin in 6 specimens. These six 6 cases were further managed by observation (n = 2), by further surgical excision using marginal strip (n = 2) and by Mohs' surgery (n = 2).
CONCLUSION: Marginal strip examines the entire resection margins analogous to Mohs' technique and we recommend its use in lid margin where tarsus is present throughout the specimen and >4 mm from the lid margin.

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Mesh:

Year:  2007        PMID: 17229804      PMCID: PMC1955612          DOI: 10.1136/bjo.2006.109892

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  15 in total

1.  Eyelid sebaceous gland carcinoma (SGC) treated with 'slow' Mohs' micrographic surgery.

Authors:  A Arora; R J Barlow; J M S Williamson; J M Olver
Journal:  Eye (Lond)       Date:  2004-08       Impact factor: 3.775

2.  Basal cell carcinoma on the eyelids: own experience.

Authors:  Joanna Salomon; Andrzej Bieniek; Eugeniusz Baran; Jacek C Szepietowski
Journal:  Dermatol Surg       Date:  2004-02       Impact factor: 3.398

3.  The adequacy of the surgical excision of basal cell carcinoma.

Authors:  S I Rakofsky
Journal:  Ann Ophthalmol       Date:  1973-05

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Journal:  N Engl J Med       Date:  1965-10-21       Impact factor: 91.245

5.  The biologic behavior of basal cell carcinoma: analysis of recurrence in excised basal cell carcinoma: Part II.

Authors:  D J Hauben; H Zirkin; D Mahler; M Sacks
Journal:  Plast Reconstr Surg       Date:  1982-01       Impact factor: 4.730

6.  Basal cell carcinoma: a statistical approach to rational management.

Authors:  L B Shanoff; M Spira; S B Hardy
Journal:  Plast Reconstr Surg       Date:  1967-06       Impact factor: 4.730

7.  Eyelid basal cell carcinoma: non-Mohs excision, repair, and outcome.

Authors:  S Hamada; T Kersey; V T Thaller
Journal:  Br J Ophthalmol       Date:  2005-08       Impact factor: 4.638

8.  Observations on the inadequately excised basal cell carcinomas.

Authors:  D P Sarma; C C Griffing; T G Weilbaecher
Journal:  J Surg Oncol       Date:  1984-02       Impact factor: 3.454

9.  The Australian Mohs database, part II: periocular basal cell carcinoma outcome at 5-year follow-up.

Authors:  Raman Malhotra; Shyamala C Huilgol; Nghi T Huynh; Dinesh Selva
Journal:  Ophthalmology       Date:  2004-04       Impact factor: 12.079

10.  Microscopie-controlled excision of cutaneous tumors: chemosurgery, fresh tissue technique.

Authors:  T A Tromovitch; S J Stegman
Journal:  Cancer       Date:  1978-02       Impact factor: 6.860

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