| Literature DB >> 17229502 |
Valérie Caro, Valérie Bouchez, Nicole Guiso, Blanca Gatti, Maria Rosa Agosti, Silvia E Gonzàlez Ayala.
Abstract
We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IVbeta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine.Mesh:
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Year: 2006 PMID: 17229502 DOI: 10.1016/j.vaccine.2006.08.024
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641