| Literature DB >> 1722950 |
G Werner-Felmayer1, E R Werner, D Fuchs, A Hausen, G Reibnegger, H Wachter.
Abstract
IFN-gamma is the most effective principle responsible for IDO induction in human cells in vitro. Lymphocyte factors support the effect of other IFN species. Induction of IDO and influence of various factors on IDO is correlated to pteridine synthesis. Cooperative effects of several mediators may account for in vivo observations concerning enhanced excretion of neopterin and tryptophan metabolites in certain disease states.Entities:
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Year: 1991 PMID： 1722950 DOI： 10.1007/978-1-4684-5952-4_55
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622