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Literature DB >> 1722784

Cefminox sodium penetration into prostatic tissue with and without inflammation.

Abstract

The concentrations of cefminox sodium (CMNX) in serum and prostatic tissue were determined in 36 cases of prostatic hyperplasia with and without inflammation. Mean ratios of CMNX in tissue over concentration in serum were 0.11 +/- 0.07 for patients with inflammation and 0.09 +/- 0.06 for those without inflammation. There was no significant difference between the two groups. These data suggest that CMNX penetration into prostatic tissue is not influenced by the presence of inflammation.

Entities: Chemical Disease Species

Mesh：

Substances：
Cephamycins
cefminox

Year: 1991 PMID： 1722784 DOI： 10.1007/bf02549847

Source DB: PubMed Journal: Int Urol Nephrol ISSN： 0301-1623 Impact factor: 2.370

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References

7 in total

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Journal: Eur J Clin Microbiol Date: 1984-12 Impact factor: 3.267

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Journal: J Antibiot (Tokyo) Date: 1983-03 Impact factor: 2.649

Cefminox sodium penetration into prostatic tissue with and without inflammation.

1. Chronic bacterial prostatitis and the diffusion of drugs into prostatic fluid.

2. A novel method to predict the elimination half-lives and the renal excretion mechanisms of cephalosporins.

3. The penetration of antibiotics into the prostate in chronic bacterial prostatitis.

4. Synthesis and biological activity of 7 beta-(2-amino-2-carboxy)-ethylthioacetamido-7 alpha-methoxycephalosporin derivatives.

5. Prostatitis syndromes: new perspectives about old woes.

6. Chronic bacterial prostatitis: 10 years of experience with local antibiotics.

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