Bufadienolides from Urginea maritima sensu strictu.

Fourteen bufadienolides were isolated from bulbs of hexaploid URGINEA MARITIMA (L.) Baker SENSU STRICTU. The compounds were identified by means of FAB-MS, (1)-NMR and (13)C-NMR studies or comparison with authentic substances. Besides the already known proscillaridin A, scillaren A, glucoscillaren A, scilliphaeoside, glucoscilliphaeoside, 12- EPI-scilliphaeoside, gamabufotalin-3- O-alpha- L-rhamnoside, 16beta- O-acetyl-gamabufotalin-3- O-alpha- L-rhamnoside, scilliglaucoside, and scillicyanoside, four new bufadienolides were isolated: 5alpha-4,5-dihydroproscillaridin A, 5alpha-4,5-dihydroglucoscillaren A, gamabufotalin-3- O-alpha- L-rhamnosido-beta- D-glucoside, and 19-oxo-5alpha-4,5-dihydro-proscillaridin A.