Literature DB >> 17224850

Detecting unsuspected HIV infection with a rapid whole-blood HIV test in an urban emergency department.

Sheryl B Lyss1, Bernard M Branson, Karen A Kroc, Eileen F Couture, Daniel R Newman, Robert A Weinstein.   

Abstract

OBJECTIVE: To evaluate and compare HIV screening and provider-referred diagnostic testing as strategies for detecting undiagnosed HIV infection in an urban emergency department (ED).
METHODS: From January 2003 through April 2004, study staff offered HIV screening with rapid tests to ED patients regardless of risks or symptoms. ED providers could also refer patients for diagnostic testing. Patients aged 18 to 54 years without known HIV infection were eligible.
RESULTS: Of 4849 eligible patients approached for screening, 2824 (58%) accepted and were tested; 414 (95%) of 436 provider-referred patients accepted and were tested. Thirty-five (1.2%) screened patients and 48 (11.6%) provider-referred patients were infected with HIV (P < 0.001). Of these, 18 (51%) screened patients and 24 (50%) referred patients reported no traditional risk factors; 27 (77%) screened patients and 38 (79%) referred patients entered HIV care. Of HIV-infected patients with CD4 cell counts available, 14 (45%) of 31 screened patients and 37 (82%) of 45 provider-referred patients had <200 cells/microL (P < 0.001).
CONCLUSIONS: ED screening detects HIV infection and links to care patients who may not be tested through risk- or symptom-based strategies. The diagnostic yield was higher among provider-referred patients, but screening detected patients earlier in the course of disease.

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Year:  2007        PMID: 17224850     DOI: 10.1097/QAI.0b013e31802f83d0

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  50 in total

Review 1.  Time to move towards opt-out testing for HIV in the UK.

Authors:  M Hamill; K Burgoine; F Farrell; J Hemelaar; G Patel; D E Welchew; H W Jaffe
Journal:  BMJ       Date:  2007-06-30

2.  Expanding Hospital Human Immunodeficiency Virus Testing in the Bronx, New York and Washington, District of Columbia: Results From the HPTN 065 Study.

Authors:  Bernard M Branson; Pollyanna R Chavez; Brett Hanscom; Elizabeth Greene; Laura McKinstry; Kate Buchacz; Geetha Beauchamp; Theresa Gamble; Barry S Zingman; Edward Telzak; Tammey Naab; Lisa Fitzpatrick; Wafaa M El-Sadr
Journal:  Clin Infect Dis       Date:  2018-05-02       Impact factor: 9.079

3.  Demographic variations in HIV testing history among emergency department patients: implications for HIV screening in US emergency departments.

Authors:  Roland C Merchant; Bethany M Catanzaro; George R Seage; Kenneth H Mayer; Melissa A Clark; Victor G Degruttola; Bruce M Becker
Journal:  J Med Screen       Date:  2009       Impact factor: 2.136

4.  Emergency department patient acceptance of opt-in, universal, rapid HIV screening.

Authors:  Roland C Merchant; George R Seage; Kenneth H Mayer; Melissa A Clark; Victor G DeGruttola; Bruce M Becker
Journal:  Public Health Rep       Date:  2008 Nov-Dec       Impact factor: 2.792

5.  Nomenclature and definitions for emergency department human immunodeficiency virus (HIV) testing: report from the 2007 conference of the National Emergency Department HIV Testing Consortium.

Authors:  Michael S Lyons; Christopher J Lindsell; Jason S Haukoos; Gregory Almond; Jeremy Brown; Yvette Calderon; Eileen Couture; Roland C Merchant; Douglas A E White; Richard E Rothman; Chris Aldridge; Gregory Almond; Gregory Andrade; Christian Arbelaez; Tom-meka Archinard; Steven I Aronin; Susan Barrera; Moses Bateganya; Joanna Bell-Merriam; Bob Bongiovanni; Kathleen Brady; Bernard Branson; Carol Brosgart; Jeremy Brown; Evan Cadoff; Yvette Calderon; Linda Chaille-Arnold; Ben Cheng; William Chiang; Brittney Copeland; Rosalyn L Cousar; Eileen Couture; Maggie Czarnogorski; Kit Delgado; Emily Erbelding; James Feldman; Osvaldo Garcia; Charlotte A Gaydos; Nancy Glick; Barbara Gripshover; Jason Haukoos; Alisa Hayes; James Heffelfinger; Laura Herrera; Amy Hilley; David Holtgrave; Brooke Hoots; Emily Hopkins; Debra Houry; Debra Howell; Yu-Hsiang Hsieh; Angela B Hutchinson; Blanca Jackson; Michael Jaker; Kerin Jones; Juliana Jung; Linda Kampe; Virginia Kan; Nancy Kass; Gabor D Kelen; Karen Kroc; Ann Kurth; Margaret A Lampe; Jason Leider; Michael Lemanski; Christopher J Lindsell; Michael Lyons; Sandra McGovern; Seth Mercer; Roland Merchant; Nancy Miertschin; Joan Miller; Patricia Mitchell; Sarah Nelson; Linda Onaga; David Paltiel; Sindy Paul; Harold Pollack; Stephen Raffanti; Liisa Randall; Richard Rothman; Akhter Sabreen; Jeffrey Sankoff; Vanessa Sasso; Nathaniel Bernard Saylor; Elissa Schechter; Barbara Schechtman; Steven Schrantz; Alicia Scribner; Judy Shahan; Daniel Skiest; Freya Spielberg; Irijah S Stennett; Patrick Sullivan; Cathalene Teahan; Susan Thompson; Gretchen Torres; Vicken Totten; Krystn Wagner; Rochelle Walensky; Michael Waxman; Andrea Weddle; Douglas White; Tom Widell; James A Wilde; Keith Wrenn; Juliet Yonek
Journal:  Acad Emerg Med       Date:  2008-12-06       Impact factor: 3.451

6.  Is self-perceived HIV risk congruent with reported HIV risk among traditionally lower HIV risk and prevalence adult emergency department patients? Implications for HIV testing.

Authors:  Kimberly Pringle; Roland C Merchant; Melissa A Clark
Journal:  AIDS Patient Care STDS       Date:  2013-10       Impact factor: 5.078

7.  HIV testing and referral to care in U.S. hospitals prior to 2006: results from a national survey.

Authors:  Gretchen Williams Torres; Juliet Yonek; Jeremy Pickreign; Heidi Whitmore; Romana Hasnain-Wynia
Journal:  Public Health Rep       Date:  2009 May-Jun       Impact factor: 2.792

8.  Effectiveness of increasing emergency department patients' self-perceived risk for being human immunodeficiency virus (HIV) infected through audio computer self-interview-based feedback about reported HIV risk behaviors.

Authors:  Roland C Merchant; Melissa A Clark; Thomas J Langan; George R Seage; Kenneth H Mayer; Victor G DeGruttola
Journal:  Acad Emerg Med       Date:  2009-11       Impact factor: 3.451

9.  Revising expectations from rapid HIV tests in the emergency department.

Authors:  Rochelle P Walensky; Christian Arbelaez; William M Reichmann; Ron M Walls; Jeffrey N Katz; Brian L Block; Matthew Dooley; Adam Hetland; Simeon Kimmel; Jessica D Solomon; Elena Losina
Journal:  Ann Intern Med       Date:  2008-08-05       Impact factor: 25.391

10.  Rapid HIV testing program implementation: lessons from the emergency department.

Authors:  Christian Arbelaez; Brian Block; Elena Losina; Elizabeth A Wright; William M Reichmann; Regina Mikulinsky; Jessica D Solomon; Matthew M Dooley; Rochelle P Walensky
Journal:  Int J Emerg Med       Date:  2009-09-01
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