OBJECTIVE: To define the rate of complications from surgery following intensive chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck. DESIGN: The medical records of 131 consecutive patients treated with a combination of chemotherapy and radiation therapy for head and neck squamous cell carcinoma from 1995 through 2002 were reviewed. Thirty-eight patients underwent 50 surgical procedures. Thirty-seven neck dissections were performed either for persistent disease, initial neck stage N2 or greater, recurrent disease, or electively as part of salvage surgery for the primary site. Thirteen salvage operations were performed for persistent or recurrent disease at the primary site. SETTING: Academic tertiary care referral center. PATIENTS: A total of 131 consecutive patients treated with a combination of chemotherapy and radiation therapy for head and neck squamous cell carcinoma (mean age at diagnosis, 53 years). MAIN OUTCOME MEASURE; Rate of complications from surgery. RESULTS: Wound complications occurred in 4 (11%) of 38 patients and 5 (10%) of 50 procedures. Major wound complications occurred in 3 (8%) of 38 patients. Minor wound complications occurred in 2 patients (5%). CONCLUSION: Surgery can be safely performed after intensive chemoradiotherapy.
OBJECTIVE: To define the rate of complications from surgery following intensive chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck. DESIGN: The medical records of 131 consecutive patients treated with a combination of chemotherapy and radiation therapy for head and neck squamous cell carcinoma from 1995 through 2002 were reviewed. Thirty-eight patients underwent 50 surgical procedures. Thirty-seven neck dissections were performed either for persistent disease, initial neck stage N2 or greater, recurrent disease, or electively as part of salvage surgery for the primary site. Thirteen salvage operations were performed for persistent or recurrent disease at the primary site. SETTING: Academic tertiary care referral center. PATIENTS: A total of 131 consecutive patients treated with a combination of chemotherapy and radiation therapy for head and neck squamous cell carcinoma (mean age at diagnosis, 53 years). MAIN OUTCOME MEASURE; Rate of complications from surgery. RESULTS: Wound complications occurred in 4 (11%) of 38 patients and 5 (10%) of 50 procedures. Major wound complications occurred in 3 (8%) of 38 patients. Minor wound complications occurred in 2 patients (5%). CONCLUSION: Surgery can be safely performed after intensive chemoradiotherapy.
Authors: William Scotton; Richard Cobb; Leo Pang; Iain Nixon; Anil Joshi; Jeanne-Pierre Jeannon; Richard Oakley; Gary French; Carolyn Hemsley; Ricard Simo Journal: Eur Arch Otorhinolaryngol Date: 2012-01-25 Impact factor: 2.503
Authors: Ian Ganly; Jennifer Bocker; Diane L Carlson; Salvatore D'Arpa; Maria Coleman; Nancy Lee; David G Pfister; Jatin P Shah; Snehal G Patel Journal: Head Neck Date: 2010-11-04 Impact factor: 3.147
Authors: N R Dean; L Sweeny; P M Harari; J A Bonner; V Jones; L Clemons; H Geye; E L Rosenthal Journal: J Wound Care Date: 2011-04 Impact factor: 2.072
Authors: R Pellini; G Mercante; C Marchese; V Terenzi; I Sperduti; V Manciocco; P Ruscito; G Cristalli; P Marchesi; B Pichi; G Spriano Journal: Acta Otorhinolaryngol Ital Date: 2013-02 Impact factor: 2.124
Authors: Patricia L Kearney; John M Watkins; Keisuke Shirai; Amy E Wahlquist; John A Fortney; Elizabeth Garrett-Mayer; M Boyd Gillespie; Anand K Sharma Journal: Mcgill J Med Date: 2011-06
Authors: L Putten; R Bree; P A Doornaert; J Buter; S E J Eerenstein; D H F Rietveld; D J Kuik; C R Leemans Journal: Acta Otorhinolaryngol Ital Date: 2015-06 Impact factor: 2.124