| Literature DB >> 17224398 |
D Grahame Hardie1, Bruno G Frenguelli.
Abstract
The cellular energy-sensing kinase AMPK is known to be activated in neurons in response to metabolic insults, but the downstream consequences have been unclear. A study by Kuramoto and colleagues in this issue of Neuron favors the idea that AMPK activation is neuroprotective, and suggests a potential mechanism for this effect involving phosphorylation of the GABA(B) receptor.Entities:
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Year: 2007 PMID： 17224398 DOI： 10.1016/j.neuron.2007.01.004
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173