Literature DB >> 17222647

Limitations of laparoscopy for bilateral nephrectomy for autosomal dominant polycystic kidney disease.

Michael C Lipke1, Vladislav Bargman, Martin Milgrom, Chandru P Sundaram.   

Abstract

PURPOSE: We retrospectively studied outcomes following bilateral hand assisted laparoscopic nephrectomy.
MATERIALS AND METHODS: We retrospectively reviewed the charts of 18 patients with symptomatic autosomal dominant polycystic kidney disease who underwent bilateral hand assisted laparoscopic nephrectomy. Preoperative radiographic imaging was reviewed retrospectively to determine kidney size based on an ellipsoid shape. A visual analog pain scale with scores of 0 to 10 to assess pain related to autosomal dominant polycystic kidney disease was measured preoperatively and postoperatively.
RESULTS: Average patient age was 48.2 years (range 30 to 64). Of the patients 14 successfully underwent bilateral hand assisted laparoscopic nephrectomy, while 4 required open conversion. A total of 16 patients underwent nephrectomy for pain and 2 underwent surgery for frequent recurrent symptomatic urinary tract infections. All patients except 1 underwent renal transplantation before bilateral nephrectomy. There was a significant difference in the volume of the right and left kidneys between the hand assisted laparoscopic and open groups (mean +/- SD 1,043 +/- 672 and 1,058 +/- 603.8 vs 4,052 +/- 548 and 3,592 +/- 1,752 cm(3), p <0.001 and 0.06 respectively). There were 5 complications, including wound infection and protracted ileus in 2 patients each, and incisional hernia in 1. In addition, the difference in mean preoperative and postoperative visual analog pain scores was statistically significant (6.9, range 3 to 10 and 0.5, range 0 to 2, p <0.05).
CONCLUSIONS: Bilateral laparoscopic hand assisted nephrectomy is a safe and reliable option in patients requiring removal of the 2 kidneys in a single setting. Rather than performing staged nephrectomies, hand assisted laparoscopic nephrectomy allows the single administration of general anesthesia and provides effective relief of bothersome symptoms in patients with symptomatic autosomal dominant polycystic kidney disease. This procedure is safe in patients with renal transplants. Patients with massive polycystic kidneys with a kidney volume of greater than 3,500 cc are at increased risk for open conversion and they may have improved outcomes if open nephrectomy is attempted from the outset.

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Year:  2007        PMID: 17222647     DOI: 10.1016/j.juro.2006.09.026

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  29 in total

Review 1.  Autosomal dominant polycystic kidney disease: the last 3 years.

Authors:  Vicente E Torres; Peter C Harris
Journal:  Kidney Int       Date:  2009-05-20       Impact factor: 10.612

2.  Volume regression of native polycystic kidneys after renal transplantation.

Authors:  Yeonsoon Jung; María V Irazabal; Fouad T Chebib; Peter C Harris; Patrick G Dean; Mikel Prieto; Fernando G Cosio; Ziad M El-Zoghby; Vicente E Torres
Journal:  Nephrol Dial Transplant       Date:  2015-06-04       Impact factor: 5.992

3.  Native nephrectomy in transplant patients with autosomal dominant polycystic kidney disease.

Authors:  P Patel; C Horsfield; F Compton; J Taylor; G Koffman; J Olsburgh
Journal:  Ann R Coll Surg Engl       Date:  2011-07       Impact factor: 1.891

Review 4.  Evaluation and management of pain in autosomal dominant polycystic kidney disease.

Authors:  Marie C Hogan; Suzanne M Norby
Journal:  Adv Chronic Kidney Dis       Date:  2010-05       Impact factor: 3.620

5.  Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Authors:  Arlene B Chapman; Olivier Devuyst; Kai-Uwe Eckardt; Ron T Gansevoort; Tess Harris; Shigeo Horie; Bertram L Kasiske; Dwight Odland; York Pei; Ronald D Perrone; Yves Pirson; Robert W Schrier; Roser Torra; Vicente E Torres; Terry Watnick; David C Wheeler
Journal:  Kidney Int       Date:  2015-03-18       Impact factor: 10.612

6.  Laparoscopic nephrectomy for massive polycystic kidney disease: Updated technique and outcomes.

Authors:  Rahul Kumar Bansal; Anil Kapoor
Journal:  Can Urol Assoc J       Date:  2014-09       Impact factor: 1.862

7.  Bilateral Nephrectomy in Patients with Autosomal Dominant Polycystic Kidney Disease and End-Stage Chronic Renal Failure.

Authors:  Alexander E Lubennikov; Nicolay V Petrovskii; German E Krupinov; Evgeniy M Shilov; Roman N Trushkin; Oleg N Kotenko; Petr V Glybochko
Journal:  Nephron       Date:  2021-02-05       Impact factor: 2.847

Review 8.  Renal artery embolization-indications, technical approaches and outcomes.

Authors:  Arnaud Muller; Olivier Rouvière
Journal:  Nat Rev Nephrol       Date:  2014-12-23       Impact factor: 28.314

Review 9.  Tailoring the 'Perfect Fit' for Renal Transplant Recipients with End-stage Polycystic Kidney Disease: Indications and Timing of Native Nephrectomy.

Authors:  Chrysoula Argyrou; Demetrios Moris; Spyridon Vernadakis
Journal:  In Vivo       Date:  2017 May-Jun       Impact factor: 2.155

10.  Pertinent issues in pretransplant recipient workup.

Authors:  Pranjal Modi
Journal:  Indian J Urol       Date:  2007-07
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