| Literature DB >> 17222165 |
Abstract
An increased understanding of the genetic, molecular and cellular mechanisms responsible for the development of polycystic kidney disease has laid out the foundation for the development of rational therapies. Many animal models where these therapies can be tested are currently available. This review summarizes the rationale for these treatments, the results of preclinical trials and the prospects for clinical trials, some already in early phases of implementation.Entities:
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Year: 2007 PMID： 17222165 DOI： 10.1111/j.1365-2796.2006.01743.x
Source DB: PubMed Journal: J Intern Med ISSN： 0954-6820 Impact factor: 8.989