| Literature DB >> 17220990 |
Alex M Chen1, Martha E Ellison, Andrey Peresypkin, Robert M Wenslow, Narayan Variankaval, Cecile G Savarin, Theresa K Natishan, David J Mathre, Peter G Dormer, Danielle H Euler, Richard G Ball, Zhixiong Ye, Yaling Wang, Ivan Santos.
Abstract
We report the first case of a pharmaceutical cocrystal formed between an inorganic acid and an active pharmaceutical ingredient (API), which enabled us to develop a stable crystalline and bioavailable solid dosage form for pharmaceutical development where otherwise only unstable amorphous free form or salts could have been used.Entities:
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Year: 2006 PMID： 17220990 DOI： 10.1039/b612353h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222