Literature DB >> 17220972

Alternative donor substrates for inverting and retaining glycosyltransferases.

Luke L Lairson1, Warren W Wakarchuk, Stephen G Withers.   

Abstract

By the use of glycosyl donors containing aromatic leaving groups linked with opposite anomeric configurations compared to those of the natural donor substrates, an inverting (Cst II) and a retaining (LgtC) glycosyltransferase were found to catalyse glycosylation reactions of natural acceptor substrates in the presence of the corresponding nucleotide.

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Year:  2006        PMID： 17220972     DOI： 10.1039/b614636h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Structural and mechanistic analysis of a β-glycoside phosphorylase identified by screening a metagenomic library.

Authors:  Spencer S Macdonald; Ankoor Patel; Veronica L C Larmour; Connor Morgan-Lang; Steven J Hallam; Brian L Mark; Stephen G Withers
Journal:  J Biol Chem       Date:  2018-01-09       Impact factor: 5.157

2.  Glycobiology: Challenging reaction equilibria.

Authors:  Robert A Field
Journal:  Nat Chem Biol       Date:  2011-09-19       Impact factor: 15.040

3.  A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis.

Authors:  Jianjun Zhang; Shanteri Singh; Ryan R Hughes; Maoquan Zhou; Manjula Sunkara; Andrew J Morris; Jon S Thorson
Journal:  Chembiochem       Date:  2014-03-21       Impact factor: 3.164

4.  Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning.

Authors:  Jianjun Zhang; Ryan R Hughes; Meredith A Saunders; Sherif I Elshahawi; Larissa V Ponomareva; Yinan Zhang; Sydney R Winchester; Samantha A Scott; Manjula Sunkara; Andrew J Morris; Mark A Prendergast; Khaled A Shaaban; Jon S Thorson
Journal:  J Nat Prod       Date:  2016-12-28       Impact factor: 4.050

5.  Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis.

Authors:  Richard W Gantt; Pauline Peltier-Pain; Shanteri Singh; Maoquan Zhou; Jon S Thorson
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-22       Impact factor: 11.205

6.  Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides.

Authors:  Jiansong Cheng; Shengshu Huang; Hai Yu; Yanhong Li; Kam Lau; Xi Chen
Journal:  Glycobiology       Date:  2009-10-30       Impact factor: 4.313

7.  Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation.

Authors:  Pauline Peltier-Pain; Karen Marchillo; Maoquan Zhou; David R Andes; Jon S Thorson
Journal:  Org Lett       Date:  2012-09-17       Impact factor: 6.005

8.  Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities.

Authors:  Jiansong Cheng; Hai Yu; Kam Lau; Shengshu Huang; Harshal A Chokhawala; Yanhong Li; Vinod Kumar Tiwari; Xi Chen
Journal:  Glycobiology       Date:  2008-05-28       Impact factor: 4.313

9.  Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions.

Authors:  Richard W Gantt; Pauline Peltier-Pain; William J Cournoyer; Jon S Thorson
Journal:  Nat Chem Biol       Date:  2011-08-21       Impact factor: 15.040

Review 10.  Leloir Glycosyltransferases in Applied Biocatalysis: A Multidisciplinary Approach.

Authors:  Luuk Mestrom; Marta Przypis; Daria Kowalczykiewicz; André Pollender; Antje Kumpf; Stefan R Marsden; Isabel Bento; Andrzej B Jarzębski; Katarzyna Szymańska; Arkadiusz Chruściel; Dirk Tischler; Rob Schoevaart; Ulf Hanefeld; Peter-Leon Hagedoorn
Journal:  Int J Mol Sci       Date:  2019-10-23       Impact factor: 5.923
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